SKU: 72173539502

DM Formula™

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Description

DM Formula™How it Works Degenerative myelopathy (DM) is a frustrating and heartbreaking condition for which modern medicine has no cure. Most veterinarians typically have nothing to offer. Even the help of trained rehabilitation therapists may not be enough to stop the heartbreaking progression to complete paralysis. What if that decline could be halted? What if we could even turn back the clock a little bit in DM dogs? DM used to be described as doggy MS, but

How it Works

Degenerative myelopathy (DM) is a frustrating and heartbreaking condition for which modern medicine has no cure. Most veterinarians typically have nothing to offer. Even the help of trained rehabilitation therapists may not be enough to stop the heartbreaking progression to complete paralysis. What if that decline could be halted? What if we could even turn back the clock a little bit in DM dogs?

DM used to be described as ‘doggy MS’, but the disease is much more like the human disease known as ALS. Dogs with DM have a mutation in the gene that codes for the SOD-1 (superoxide dismutase) enzyme. Instead of acting as an antioxidant, the enzyme creates “excitotoxicity” by causing a build up of glutamate in the spinal cord. As in ALS, that build up is toxic to nerves, causing them to slowly die.

There’s no highly effective drug for ALS that we can borrow for the treatment of DM, but plenty of research has demonstrated the possible utility of plants for the condition.

Laboratory testing has shown that certain herbs can help decrease SOD in tissues and help protect neurons from dying from excess glutamate. We’ve integrated some of the most powerful of them into the DM Formula, which is an adaptation of the two-thousand-year-old formula known as Minor Bupleurum Combination (Xiao Chai Hu Tang).

If mutant SOD levels can be lowered and glutamate-induced injury mitigated, neurons in DM dogs that have not been fatally injured may return to some degree of normal function. Disease progression might be halted, and some animals may experience a return of strength and coordination.

Stabilization and improvement of DM dogs may be more likely if the patient is fed a real food diet that lowers the risk of oxidative stress and spinal cord inflammation. Improvement is also more likely if the patient is under the care of a rehabilitation therapist or physiotherapist. Specific treatments that may help include mobilization of the spine using massage and gentle chiropractic; the reduction of cord inflammation using anti-inflammatory acupuncture and laser treatments; and the reduction of oxidative stress using ozone therapy.

Ingredients


  • Bupleurum root
  • Ginseng root
  • Rhubarb root and rhizome
  • Ginger rhizome
  • Pinellia rhizome
  • Jujube
  • Salvia root
  • Scutellaria root
  • Natural flavouring

Dosing  

DM Formula is an organically grown concentrated herbal extract in powdered form. DM Formula acts more quickly and completely if your pet is fed a real food meat- and vegetable-based diet, and if they receive physical therapies like chiropractic, acupuncture, massage, PEMF and laser therapy by a practitioner knowledgeable in the unique pathophysiology of DM.

To use, just fold the herbs into your pet's real food diet or shake them up with broth or water and pour them over top if using canned or kibble.

As a suggested starting dose, give twice daily as follows:

  • Up to 15 pounds: 1/8 tsp
  • 15 to 40 pounds: 1/4 tsp
  • 40 to 70 pounds: 1/2 tsp
  • 70 to 110 pounds: 3/4 tsp
  • Over 110 pounds: 1 tsp

If benefits are not seen, the dose can be safely doubled.

One bottle of Cessorex lasts over a month for dogs 50 lbs and under; and for two weeks for 100 lb dogs

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SKU: 72173539502

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San Leandro, US
★★★★★ 5
Stylish comfy shoes
Size: 11.5, Color: Black
My husband adores these shoes. They are true to size. Comfy and stylish and lightweight which makes the ideal combo for him. Glad I purchased them.
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Reviewed in the United States on September 30, 2025
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Steve C
Charlottesville, US
★★★★★ 5
Good shoe!
Size: 12, Color: Black
Comfortable shoes for someone with wider feet and challenges finding comfortable dress loafers! Good price for the quality and comfort! Have two pairs
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Reviewed in the United States on December 29, 2025
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SirTW
Battle Creek, US
★★★★★ 5
Sleek, upscale and supremely comfortable
Size: 9, Color: Cognac
I did not know that Marc Joseph makes hands free slip ins. I own four pair of Skechers, and I thought they were the only game in town. I decided that I wanted a pair of business casual pair of wingtips. I already own two pair of Skechers Mark Nason wingtips in blue and black nubuck, so I bought a pair of their cognac colored. Perfectly fine shoes, but when they arrived, I didn't like the color, so the search was on! I found these cognac-colored Mark Joseph's and hands down, they fit the bill for what I was looking for! I actually bought two more pair of Skechers in the brown family in the same oxford, elastic lace style: One pair of another style of their Mark Nason line and one pair of their Garza line. So now I am comparing three pair of Skechers to the Marc Joseph's. Obsessive, I know :). Luckily, I have a Skechers store near me for easy returns. The look I was going for is a sleek, business casual that I could dress up or down. Three things that I love about the Marc Joseph's are the beautiful cognac finish: the white yet lower profile soles and the more formal, narrower toe style. The MJ's nailed it with the color. They have a slightly darker, more lustrous and glossier look than the others. The color alone looks classier and pairs well with black pants which I wear for work almost every day. The white soles are exactly what I was looking for. The visible rise is probably about a third of the thickness of the others and are a much more subtle, classier look. They offset the cognac color nicely but are not that in your face, sneaker looking, thick white sole. When I was comparing them to the others right out of the box, I thought they would be too narrow and tight because they looked sleeker and narrower than the others. But they fit perfectly and were very comfortable right out of the box. Upon closer inspection and comparison, I realized the narrower, sleeker look is because the eyelets for the elastic shoelaces are closer together that give the illusion that the shoe is narrower. They compensate for what might create a tighter fit across the top of your foot with two stretchy "gores" they are called on either side of the upper part. The "slits" are nicely finished, and you can't see the stretchy part and add a nice design touch to the shoe. But between them and the elastic shoelaces, they must stretch just enough to make them extremely comfortable across the top. So, if you have a high instep/arch, they should accommodate it nicely. Last but not least, they are very comfortable shoes. I wear a size 8 1/2 to 9 and my foot is slightly on the wide side. I bought the size 9's and they fit perfectly. If you are between sizes or have wider feet, you may want to size up a half size. Because the Skechers have much thicker soles, they might be slightly more cushioned, but the MJ's are cushioned more than enough for my purposes and very comfortable. Plus, they actually just feel better on my feet. I can't speak to how durable they will be as I just got them, but so far, so good. So, there you have it. I rely on other people's reviews a lot when buying online, and especially for shoes. I know it's always a crap shoot, particularly when buying shoes online, so I hope this review helps. Everybody's feet are different, but I highly recommend these.
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Reviewed in the United States on March 15, 2025
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Ben
Grantham, US
★★★★★ 5
Comfortable and look great!
Size: 10.5, Color: Cognac
Very comfortable, look nice, and slip on easily.
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Reviewed in the United States on June 4, 2026
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Patricia
Birmingham, US
★★★★★ 5
comfortable
Size: 10.5, Color: Cognac
comfortable and good looking
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Reviewed in the United States on June 9, 2026

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