HM-DSR Capsules

HM-DSR Capsule – Domperidone and Rabeprazole | Treatment for Acid Reflux, GERD, Heartburn, Peptic Ulcers and Digestive Disorders | Herbal Maza

HM-DSR Capsule is a clinically proven gastrointestinal medication by Herbal Maza containing a precisely formulated combination of two active pharmaceutical ingredients — Domperidone and Rabeprazole. This dual-action formulation is specifically indicated for the treatment of gastroesophageal reflux disease (GERD), acid reflux, heartburn, peptic ulcers, indigestion (dyspepsia), nausea, vomiting, and a range of other gastrointestinal disorders. By combining a proton pump inhibitor with a dopamine antagonist, HM-DSR provides simultaneous acid reduction and symptom control for comprehensive digestive relief.

HM-DSR is a pharmaceutical medication. It should only be taken as prescribed by a qualified healthcare professional. Do not self-medicate. Always follow your doctor's instructions regarding dosage, duration, and frequency of use.

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What Is HM-DSR Capsule?

HM-DSR Capsule contains a combination of Rabeprazole — a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach — and Domperidone — a dopamine antagonist that controls nausea, vomiting, and promotes gastric motility. Together, these two active ingredients work synergistically to address both the root cause of acid-related disorders (excess stomach acid) and the associated symptoms (nausea, vomiting, and gastric discomfort) in a single convenient capsule.

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Indications – What Conditions Does HM-DSR Treat?

HM-DSR Capsule is indicated for the following gastrointestinal conditions:

• Gastroesophageal Reflux Disease (GERD) – Treats GERD both with and without associated ulcers by reducing stomach acid production and alleviating reflux symptoms.
• Acid Reflux and Heartburn – Reduces the frequency and severity of acid reflux episodes and the burning sensation (heartburn) in the chest and throat.
• Peptic Ulcers and Stomach Ulcers – Supports the healing of peptic ulcers by reducing the acid environment that prevents ulcer recovery.
• Duodenal Ulcers – Prevents the formation and recurrence of ulcers in the upper part of the small intestine (duodenum).
• Indigestion (Dyspepsia) – Reduces stomach discomfort, bloating, fullness, and pain associated with functional or acid-related dyspepsia.
• Nausea and Vomiting – Domperidone effectively treats symptoms of nausea and vomiting in adults and in children above 12 years of age weighing 35 kg or more.
• Zollinger-Ellison Syndrome – Manages the excessive acid production associated with this rare but serious condition through sustained proton pump inhibition.
• Excess Stomach Acid Production – Directly reduces the amount of acid produced by the stomach lining through Rabeprazole's proton pump inhibition mechanism.
• General Digestive Discomfort – Improves overall digestive health and reduces associated discomfort from acid-related gastrointestinal disorders.

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How Does HM-DSR Work? – Mechanism of Action

Rabeprazole – Proton Pump Inhibitor (PPI)

Rabeprazole belongs to the proton pump inhibitor (PPI) class of medications. It works by irreversibly binding to and blocking the hydrogen-potassium ATPase enzyme system (the proton pump) in the stomach's parietal cells — the primary mechanism responsible for acid secretion. By blocking this pump, Rabeprazole significantly reduces the amount of hydrochloric acid produced in the stomach, creating a less acidic environment that allows ulcers to heal, prevents acid damage to the esophageal lining, and relieves the symptoms of GERD and heartburn.

Domperidone – Dopamine Antagonist and Prokinetic Agent

Domperidone is a peripheral dopamine D2 receptor antagonist that works by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) and in the gastrointestinal tract. This dual action reduces nausea and vomiting by blocking the brain's vomiting trigger signals, while simultaneously improving gastric motility — accelerating the emptying of the stomach into the small intestine and reducing the backflow of stomach contents into the esophagus. Together with Rabeprazole, it provides both acid control and symptom management in a single formulation.

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Health Guidance – Important Patient Information

Diabetic Patients

HM-DSR Capsule contains Domperidone and Rabeprazole — pharmaceutical active ingredients that do not contain sugar and do not directly affect blood glucose levels. Diabetic patients who require treatment for GERD, acid reflux, or other gastrointestinal conditions can generally use HM-DSR as prescribed by their physician. However, diabetic patients must inform their doctor about all current medications before starting HM-DSR to check for any interactions with diabetes medications.

Patients with Liver or Kidney Conditions

Both Domperidone and Rabeprazole are metabolized by the liver and excreted through the kidneys. Patients with moderate to severe liver impairment or kidney disease should use HM-DSR with caution and only under direct physician supervision with appropriate dose adjustment if required.

Patients with Heart Conditions

Domperidone has been associated with rare cardiac effects including QT interval prolongation. Patients with a known history of cardiac arrhythmia, heart disease, or those taking medications that affect the QT interval must consult their cardiologist or physician before use. HM-DSR should be used at the lowest effective dose for the shortest duration required in patients with cardiac risk factors.

Elderly Patients

Elderly patients are more likely to have reduced liver and kidney function and may be on multiple medications. They should use HM-DSR under physician supervision and with careful monitoring for any adverse effects or drug interactions.

Pregnant and Breastfeeding Women

The safety of Domperidone and Rabeprazole during pregnancy and breastfeeding has not been fully established. Pregnant or breastfeeding women must consult their obstetrician before use. Self-medication during pregnancy is strongly discouraged.

Important Note: HM-DSR is a pharmaceutical medication and must only be taken under the prescription and supervision of a qualified healthcare professional. Do not self-medicate or alter the prescribed dose without medical advice.

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Key Benefits of HM-DSR Capsule

• Treats GERD With and Without Ulcers – Dual-action formula addresses both the acid cause and the reflux symptoms of gastroesophageal reflux disease.
• Reduces Acid Reflux and Heartburn – Rabeprazole significantly reduces stomach acid production for lasting relief from reflux and burning sensations.
• Heals Peptic and Stomach Ulcers – Low acid environment created by Rabeprazole supports natural ulcer healing and prevents recurrence.
• Prevents Duodenal Ulcer Formation – Protects the upper intestinal lining from acid damage and ulcer development.
• Effectively Treats Indigestion (Dyspepsia) – Reduces bloating, fullness, stomach pain, and discomfort from functional and acid-related dyspepsia.
• Controls Nausea and Vomiting – Domperidone blocks vomiting trigger signals and improves gastric emptying for effective nausea management.
• Manages Zollinger-Ellison Syndrome – Sustained proton pump inhibition controls the excessive acid secretion characteristic of this condition.
• Improves Gastric Motility – Domperidone accelerates stomach emptying and reduces the backflow of stomach contents for better digestive function.
• Dual-Action Single Capsule Convenience – Both acid reduction and nausea control delivered in one easy-to-take capsule.
• Improves Overall Digestive Health – Comprehensive gastric acid and motility management for better comfort and quality of life.

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Who Should Use HM-DSR Capsule?

• Patients diagnosed with gastroesophageal reflux disease (GERD)
• Patients suffering from chronic or recurring acid reflux and heartburn
• Patients with peptic ulcers, stomach ulcers, or duodenal ulcers
• Patients experiencing indigestion, bloating, and dyspepsia
• Adults and children above 12 years of age (weighing 35 kg or more) with nausea and vomiting
• Patients with Zollinger-Ellison Syndrome requiring acid suppression management
• Patients prescribed this medication by their healthcare provider for any of the above indications

Who Should Avoid or Use With Caution?

• Patients with Cardiac Arrhythmia or Heart Disease – Domperidone may prolong the QT interval. Consult a cardiologist before use.
• Patients with Moderate to Severe Liver Impairment – Both active ingredients are liver-metabolized. Physician supervision and dose adjustment required.
• Patients with Kidney Disease – Consult physician before use for appropriate dose guidance.
• Children Under 12 Years of Age or Under 35 kg – Domperidone is indicated for nausea/vomiting only in children above 12 years of age weighing 35 kg or more.
• Pregnant and Breastfeeding Women – Must consult obstetrician before use.
• Patients on QT-Prolonging Medications – Including certain antifungals, antibiotics, and antiarrhythmics. Inform your doctor of all current medications.
• Patients with Known Hypersensitivity – Anyone with known allergy to Domperidone, Rabeprazole, or related compounds must not use this medication.

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Active Ingredients – Composition

• Rabeprazole – A second-generation proton pump inhibitor that binds to and irreversibly inhibits the gastric H+/K+ ATPase enzyme, reducing stomach acid secretion. Indicated for GERD, peptic ulcers, duodenal ulcers, Zollinger-Ellison Syndrome, and acid-related disorders.
• Domperidone – A peripheral dopamine D2 receptor antagonist and prokinetic agent that blocks nausea and vomiting signals at the chemoreceptor trigger zone and improves gastric emptying and motility. Indicated for nausea, vomiting, and GERD.

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Directions for Use

• Swallow the capsule whole with a full glass of water.
• Do not crush, break, or chew the capsule — the enteric coating is essential for the correct release and absorption of the active ingredients.
• Take HM-DSR exactly as prescribed by your doctor — follow the prescribed dose, frequency, and duration strictly.
• HM-DSR is typically taken before meals for optimal absorption of Rabeprazole. Follow your physician's specific timing instructions.
• Do not stop the medication early without medical advice, even if symptoms improve — completing the prescribed course is important for ulcer healing and GERD management.
• If you miss a dose, take it as soon as you remember — but if it is nearly time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.

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Storage Instructions

• Store in a cool, dry place away from direct sunlight, heat, and moisture.
• Store below 30°C unless otherwise specified on the packaging.
• Keep the container tightly closed after each use.
• Keep out of reach of children.
• Do not use after the expiry date printed on the packaging.

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Safety Information and Precautions

• Prescription Required – HM-DSR is a pharmaceutical medication. Use only under physician prescription and supervision.
• Inform Your Doctor – Before taking HM-DSR, inform your doctor of all current medications, supplements, and medical conditions including heart disease, liver disorders, kidney disease, and diabetes.
• Cardiac Monitoring – Patients with cardiac risk factors should have ECG monitoring as directed by their physician during Domperidone use.
• Long-Term Use – Prolonged use of proton pump inhibitors like Rabeprazole has been associated with reduced magnesium levels, reduced vitamin B12 absorption, and increased infection risk. Long-term use should be under physician supervision with periodic monitoring.
• Not for Self-Medication – Do not take this medication without a doctor's prescription or adjust the dose without medical advice.
• Diabetic Patients – HM-DSR does not contain sugar and generally does not directly affect blood glucose. Inform your doctor of diabetes diagnosis and all current medications before use.

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Disclaimer

HM-DSR Capsule is a pharmaceutical medication by Herbal Maza containing Domperidone and Rabeprazole. It is a prescription medicine and must only be used under the supervision and prescription of a qualified healthcare professional. This product is not intended for self-medication. The information provided here is for general informational purposes only and does not constitute medical advice. Always consult a licensed physician before starting, stopping, or altering the use of this or any other medication. Results and outcomes may vary depending on the individual patient's condition, severity of disease, other medications, and compliance with the prescribed treatment. Herbal Maza is not responsible for any misuse, self-medication, or adverse effects arising from the use of this product outside of a physician's prescription and supervision. Keep out of reach of children. Store as directed. Do not use after the expiry date.

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HM-DSR Capsule by Herbal Maza – Clinically Proven Dual-Action Relief for Acid Reflux, GERD, Ulcers and Digestive Disorders.
Available on Prescription – Consult Your Doctor Before Use.