SKU: 79511340858

Colofac

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Description

ColofacColofac Description Colofac is a medicine that helps ease the symptoms of IBS. It helps by relaxing the muscles in your intestines, which eases cramps and discomfort. It might take up to an hour to start working, and the effects can last for several hours. Essential Information What is Colofac? Colofac is a medication used to relieve symptoms of irritable bowel syndrome, often called IBS. This common condition affects your digestive system and can

Colofac Description
Colofac is a medicine that helps ease the symptoms of IBS.
It helps by relaxing the muscles in your intestines, which eases cramps and discomfort.
It might take up to an hour to start working, and the effects can last for several hours.

What is Colofac?

Colofac is a medication used to relieve symptoms of irritable bowel syndrome, often called IBS. This common condition affects your digestive system and can lead to cramps, diarrhoea, constipation, and general discomfort. While there's no cure for IBS, adjusting your diet and taking medication can help manage the symptoms.

Colofac has mebeverine hydrochloride as its active ingredient, which is an antispasmodic. IBS often causes pain, discomfort, and spasms in the digestive system. Colofac helps ease these spasms and other symptoms, making you feel more comfortable.

How does Colofac work?

IBS is a condition that impacts your lower digestive system, including the small and large intestines. When your intestines spasm, or tighten, it can lead to pain in your lower abdomen. Colofac contains mebeverine hydrochloride, an antispasmodic. This helps by relaxing the muscles in your intestines, preventing spasms.

What doses of Colofac are there?

Colofac is available in two different strengths: 135mg tablets and 200mg Modified-Release capsules.

Both have the same active ingredient, mebeverine hydrochloride, but the 200mg version is a slow-release tablet. This means it releases the medication gradually over time instead of all at once.

How long does Colofac take to work?

Colofac typically begins to take effect about an hour after you take it.

When you start feeling better, you can stop taking Colofac. However, it's best to check with our clinicians before doing so. If your symptoms haven't improved after two weeks, please get in touch with our clinician for further advice.

Making a mistake whilst taking Colofac

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, just skip the one you missed. Avoid taking two doses at once.

If you've taken more Colofac than you should have, speak to our clinicians or visit A&E if you experience any side effects.

What are the side effects of Colofac?

How does Colofac compare to other treatments?

Buscopan is another medication for managing IBS symptoms. It contains hyoscine butylbromide, an antispasmodic similar to Colofac. The main difference is that while Colofac relaxes the muscles in your intestines, Buscopan targets the muscles in your stomach, gut, and bladder. This can help ease symptoms like stomach cramps. Buscopan starts working in just 15 minutes, whereas Colofac takes about an hour to take effect.

Both treatments can help ease IBS symptoms. Based on your symptoms and personal preferences, our clinicians will suggest the most suitable option for you.

How effective is Colofac?

Can I take Colofac whilst pregnant or breastfeeding?

No, it's not advised to take Colofac while you're pregnant or breastfeeding.

Important Information

Colofac isn't right for everyone. There are a few things you should be aware of to ensure it's safe for you.

Here's all the official information about them. If anything isn't clear, please let our clinician know, and they can discuss it with you.

Colofac 135mg tablets | Colofac 200mg MR capsules

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SKU: 79511340858

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V M T R
Charlottesville, US
★★★★★ 5
Can't go wrong with Acorn for as long as they last!
Size: 12-13 Women/10.5-11.5 Men, Color: Charcoal
Acorn is just a great company all around. I had bought my husband these slippers over 20 years ago. They are still in great shape although the sole has worn in some places. But nothing's coming apart! However, I decided to replace them for him. His foot is 10.5 and they are a little hard to get on right away-of course, after over 20 years of having "worn in" the original pair, anything would feel tight. So I'm not holding this against them. They will relax with use. The only difference is that the original sole was black and these are tan. I think I would prefer the black, but since it's only being worn in the house, no big deal. My husband has really cold feet and these slippers never fail to warm his feet right up! He said they feel really soft to walk in and like the cushioning. They're not too heavy and fit him great! I have Acorn slippers myself that I've worn every single day in the house and outside to the mailbox too. They last.
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Reviewed in the United States on April 11, 2026
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Michael
Lexington, US
★★★★★ 4
Very warm.
Size: 13.5-14.5 Women/12-13 Men, Color: Navy Blue
Very warm and comfortable. A little difficult to put on with the collared top.
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Reviewed in the United States on January 19, 2026
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Cheryl
Charlottesville, US
★★★★★ 5
You won't be sorry
Size: 10.5-11.5 Women/9-10 Men, Color: Black
Great padding for comfort and terrific warmth. I bought a pair of Acorns 30 years ago and still have them. Updated to a new color and now feel the benefit of newer padding! I used the sizing listed for shoes and like the roominess for thicker sox. Well made and a joy to put on. (Wisconsin)
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Reviewed in the United States on December 25, 2025
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Bureau of Review
West Palm Beach, US
★★★★★ 5
Great Slippers
Size: 12-13 Women/10.5-11.5 Men, Color: Charcoal
Comfy, great price, looks great, fits well, size aligned, great quality. Love these slippers.
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Birmingham, US
★★★★★ 5
Extremely comfortable, leather sole. Hard to find a style.
Size: 13.5-14.5 Women/12-13 Men, Color: Navy Blue, Size: 13.5-14.5 Women/12-13 Men, Color: Navy Blue
Totally worth the price. This type of style is very hard to find, my husband had another pair a few years ago that he was never able to replace. These fit his wide feet and are very comfortable. The elastic at the ankle is not too tight. So glad I was able to find him a replacement. We bought the blue in a size 12. Love the fact that they are washable.
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