SKU: 32113580338

SkinMedica HA5® HYDRA COLLAGEN Replenish + Restore Hydrator

Sale price$172.80 Regular price$192.00
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Ships within 48 hours · Estimated delivery Jul 25 - Jul 30

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Description

SkinMedica HA5® HYDRA COLLAGEN Replenish + Restore HydratorAn Evolution in Hydration Introducing the next gen HA, now with 2X more hyaluronic acid. Enhanced with Hydra Collagen for instant hydration and smoothness, plus Advanced VITISENSCE Technology to replenish natural humectants, including HA and help restore skin's hydration reservoir. Provides immediate hydration lasting up to 48 hours. Enjoy visibly plump, dewy, and healthier looking skin with fewer lines. Silicone free Non comedogenic Sulfate free

 

An Evolution in Hydration – Introducing the next-gen HA⁵®, now with 2X more hyaluronic acid. Enhanced with Hydra Collagen for instant hydration and smoothness, plus Advanced VITISENSCE® Technology to replenish natural humectants, including HA and help restore skin's hydration reservoir.

Provides immediate hydration lasting up to 48 hours. Enjoy visibly plump, dewy, and healthier-looking skin with fewer lines.

Silicone-free • Non-comedogenic • Sulfate-free • Lightweight • Fragrance-free • Paraben-free • Pilling-free

Store at room temperature 15°C - 30°C (59°F - 86°F).

Key Benefits

  • HA⁵® Hydra Collagen Replenish + Restore Hydrator attracts and retains water for instant hydration and visibly plump, smooth skin
  • In a clinical study, patients reported they looked ~ 3 years younger by week 121
  • Clinically proven to improve hydration and support skin health by addressing the skin barrier and water-holding capacity

1. Data on file at SkinMedica®

Key Ingredients

Advanced VITISENSCE® Technology

Features a blend of nutrients found in nature, targeting existing collagens within the skin to boost hydration naturally.

  • Avocado Oil Esters - Supports skin's natural hydration and skin's water-holding abilities
  • Vitamin F - Supports skin barrier and prevents water loss
  • Passion Fruit Seed Oil - Enhances skin health and supports skin's water and nutrition flow
  • Vitis Flower Stem Extract and Lotus Sprout Extract - Protect against oxidative stress

Proprietary HA⁵® Hydra Collagen Complex

Hydration Collagen - vegan collagen that attracts and retains water for instant hydration and smoothness

 

5 Forms of HA:

  • Vectorized Time Release HA - A SkinMedica® proprietary ingredient for sustained release of HA
  • Cross-linked HA - Provides long-lasting hydration
  • Encapsulated HA - For immediate hydration
  • Noncross-linked HA - For smoothness and hydration 
  • Nano-hyaluronic acid - Soothes skin

 

How to use

  • When to Apply

    Apply twice daily— morning and at night—after cleansing and treating your skin. Use before you moisturize and apply SPF.

  • Where to Apply

    Apply to face, neck and chest, or any area needing hydration.

  • How to Apply

    Dispense 1 to 2 pumps in your palm and smooth onto the skin. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.

Behind the Formula:
Why it Works

HA⁵® Hydra Collagen Replenish + Restore Hydrator is our next level hydrator solution clinically proven to visibly improve hydration and support skin health, by improving the skin's barrier and water-holding capacity.

It has 2X more HA than the previous formulation to provide optimal, immediate hydration. It's our first and only hydrator to use our proprietary HA⁵® Hydra Collagen technology and Advanced VITISENSCE® Technology, targeting existing collagens deeper within the skin to boost hydration naturally. Provides long-term results that reduce the appearance of lines and redness.

 

Additional Information

  • What differentiates HA® Hydra Collagen Replenish + Restore Hydrator from the legacy HA® Rejuvenating Hydrator product?

    Modernizing our legacy HA⁵® formulation takes HA⁵® Hydra Collagen Replenish + Restore Hydrator to the next level of hydrator innovation. NEW Hydra Collagen is a vegan collagen that attracts and retains water for instant hydration and smoothness. ADVANCED VITISENSCE® TECHNOLOGY replenishes the natural HA, biohumectants, and hydration-boosting collagens within the skin to support the skin's hydration reservoir. Now, hydration lasts twice as long (48 hours vs 24 hours) compared to the original formulation.

  • What’s the difference between a moisturizer and a hydrator?

    A moisturizer is a cosmetic cream or lotion made with humectants or occlusive or a combination of that prevents skin dryness. A hydrator is a cosmetic treatment product that promotes epidermal health by supporting the skin’s natural biomolecules, including HA, other humectants and hydration-boosting collagens.

  • What’s the difference between dehydrated and dry skin?

    Dry skin is a skin type, while dehydration is a skin condition. In both, the skin undergoes transepidermal water loss, or evaporation of water from inside the body. With this water loss, the enzymes that normally help the skin shed cells cannot function properly, resulting in a buildup of cells that makes the skin look rough and dry, contributing to the appearance of fine lines and wrinkles. Dry skin can be genetic or a symptom of systemic disease. It is caused either by the inadequate production of oil, called sebum, or by an imbalance of fatty acids, ceramide, and cholesterol in the stratum corneum, the barrier layer of the skin. Age is also a factor since we experience a decline in a main hormone that triggers sebum production. Dehydrated skin still produces sebum, but is temporarily dry because of various factors, including environmental effects such as a dry climate, harsh detergents, or skin products. It is also caused by a temporary imbalance of fatty acids and ceramides in the skin’s barrier layer, resulting in a temporary spike in transepidermal water loss.

  • How should HA⁵®  Hydra Collagen Replenish & Restore Hydrator be used within a regimen?

    HA⁵®  Hydra Collagen Replenish & Restore Hydrator can be used with any SkinMedica® product or regimen to support hydration. It should be applied immediately before moisturizer in a normal regimen.

In Clinical Studies

  • 93% of patients reported this product made their skin look dewy and healthy at 2 weeks (n=30)

  • 93% reported skin looked visibly plumper at week 12 

  • 97% of patients agreed this product improved their skin quality at week 12 

  • 100% of patients agreed this product made them feel confident about their skin at week 12 

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 32113580338

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4.1 ★★★★★
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Verified Purchase
Lady B
Dallas, US
★★★★★ 5
Best affordable squeaker toy
Color: Crinkle Chicken (Brown), Size: Large, Color: Crinkle Chicken (Brown), Size: Large
my dog is obsessed with this toy, this has became his new comfort toy and after having this for about four months the legs are falling off but it’s very durable. The squeaker also moved from the head of the chicken to the body of the chicken but that’s after it was played with every single day. I love that it has two squeakers and it’s the perfect toy for my dog.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 6, 2026
A
Verified Purchase
Amazon Customer
Lake Worth, US
★★★★★ 5
My dogs favorite toy EVER
Color: Crinkle Chicken (Brown), Size: Large
I have a Belgian Malinois who loves any and every toy, but this one is definitely her favorite. She will walk around the house constantly carrying it in her mouth, which is honestly adorable to watch. The squeakers only lasted a couple of months, but I don’t really consider that a downside—I’m kind of grateful they didn’t last forever given how much she plays with it. It still remains one of her most-loved toys even without them. My only word of caution is that if you work from home, this toy makes a lot of crinkling noise. And I mean A LOT. It’s great for keeping the dog entertained, but it can definitely get a little frustrating for humans trying to focus or take calls. Overall, it’s been a big hit in our house and easily one of her favorite toys.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 8, 2026
A
Verified Purchase
Amazon Customer
Waukegan, US
★★★★★ 5
Super cute
Color: Bunny (Mauve), Size: Small
Super cute and fuzzy. Definitely perfect size for a puppy and not too loud. The fur is very soft and the nose is sown on not a hard piece that can be chewed on. Very good quality too.
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Reviewed in the United States on June 3, 2026
B
Verified Purchase
Buyer
Grantham, US
★★★★★ 4
Normally amazing
Color: Spiky Ball (Blue, Orange), Size: Medium
We have purchased these slightly spiky dog balls several times for our very strong jaw heavy chewer dogs and they’ve been amazing. They don’t break down they don’t get torn apart the squeakers don’t even pop out of them. So we ordered another package because we’ve lost a few outside to the lawnmower… oops and the package that got delivered today had only one ball that squeaks and the other does not. THIS IS A PROBLEM ! Unfortunately my female dog got to the new squeaking ball first and my male got to the non-squeaking ball and he was NOT happy. Basically once they claim a ball it’s theirs and the other dogs don’t go near the ball they claimed. So he’s following my female around and every time she squeaks the ball and I’m just waiting for him to attempt to take it from her causing damage to her. Normally… These are amazingly fun, tough, durable but also squeaking balls (that’s rare in a tough ball) that my dogs absolutely love. This time just got a bad batch I guess. When they squeak the dogs LOVE them. After several months of play the squeaker might break inside of the ball but the ball never comes apart or gets damaged. And we as the owners love that they don’t break down are not able to be ripped or torn even by our very strong jawed and big jaw muscle dogs. They are also great for in the house play because they’re small enough that they fit completely inside our dog‘s mouth but obviously not small enough to get swallowed so when we throw them in the house for fetch the dogs can jump up and catch them fully in their mouth so they don’t cause any damage to the walls when they hit the walls. They’re not super heavy but they’re incredibly durable. Definitely worth the price especially if you have heavy chewers or big jaw muscle dogs.
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Reviewed in the United States on April 28, 2026
M
Verified Purchase
MADDY
Omaha, US
★★★★★ 5
Best fun indestructible toy
Color: Crinkle Duck (Yellow), Size: Large
Truly indestructible no matter how much our oittie tries. She has owned it for three months works at destroying every day with no success. She carries it everywhere. Best purchase for chewer, more fun than the popular rubber heavy duty toy. Do not hesitate your pup will thank you for this fun distraction.
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Reviewed in the United States on May 30, 2026

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