PEG5000@ Fe3O4 nanoparticles (carboxyl terminal)

PEG5000@ Fe3O4 nanoparticles (carboxyl terminal)Product Name NamePEG5000@ Fe3O4 nanoparticles (carboxyl terminal) Product Overview PEGylated iron oxide nanoparticles (carboxyl terminus) are modified with PEG carboxyl terminus on the basis of oleic acid modified iron oxide prepared by high temperature pyrolysis method. Through this modification, the nanoparticles are transformed from oil phase to water phase, thereby expanding their applications in the biological field. Technical Parameter

Product Name

Name：PEG5000@ Fe3O4 nanoparticles (carboxyl terminal)

^{Product Overview}

PEGylated iron oxide nanoparticles (carboxyl terminus) are modified with PEG carboxyl terminus on the basis of oleic acid modified iron oxide prepared by high-temperature pyrolysis method. Through this modification, the nanoparticles are transformed from oil phase to water phase, thereby expanding their applications in the biological field.

^{Technical Parameter}

Composition: PEG2000 modified Fe3O4 magnetic nanoparticles, ultra-pure water

Diameter: ï½?0 nm

Saturation magnetization: ~60 em2/g Fe

^{Product Features}

Biocompatibility: The biocompatibility of nanoparticles has been improved by modifying them with biocompatible polyethylene glycol (PEG).

Long cycle time: PEG modification increases the circulation time of nanoparticles in vivo, which helps improve their passive targeting ability at tumor sites.

Multifunctionality: PEG has functional groups such as methoxy, carboxyl, and amino at the end, which facilitates coupling with specific targeted recognition molecules (such as antibodies, aptamers, targeting peptides, etc.) to construct targeted nanoprobes.

Contrast enhanced imaging effect: PEGylated iron oxide nanoparticles can be used for magnetic resonance imaging (MRI) to provide contrast enhanced effects.

Stability: PEG modification enhances the stability of nanoparticles, reduces immune reactions, and facilitates their use in biomedical applications.

Application Fields

Drug delivery system: PEGylation can improve the stability and blood circulation time of iron oxide nanoparticles, making them an ideal drug carrier for targeted drug delivery.

Magnetic Induction Tumor Thermotherapy (MHT): Utilizing the property of iron oxide nanoparticles generating heat under an external alternating magnetic field, it can be used to treat tumors.

Biosensing and Detection: Magnetic nanomaterials have applications in the field of biosensing, which can be used to detect biomolecules or environmental pollutants.

Theranos: A nanocarrier that combines diagnostic imaging and therapeutic functions for image-guided therapy.

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