SKU: 125030485

Mouse & Rat C3 competitive OneStep ELISA Kit

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Description

Mouse & Rat C3 competitive OneStep ELISA KitProduct Specification Antigen C3 Immunogen Recombinant Protein Antibody Type Recombinant mAb Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 6. 1% Inter assay: 10. 8% Sample type Cell culture supernatant, Serum, Plasma Assay type Competitive Sensitivity 0. 004 ug mL Range 0. 031 ug mL 2 ug mL Recovery Cell culture supernatant: 113% Serum: 108% Plasma: 102% Assay

Product Specification


Antigen C3
Immunogen Recombinant Protein
Antibody Type Recombinant mAb
Purification Protein A
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8'C as supplied.

Kit


Precision Intra-assay: 6.1%;
Inter-assay: 10.8%
Sample type Cell culture supernatant, Serum, Plasma
Assay type Competitive
Sensitivity 0.004 ug/mL
Range 0.031 ug/mL – 2 ug/mL
Recovery Cell culture supernatant: 113%
Serum: 108%
Plasma: 102%
Assay time 60 minutes
Species reactivity Ms;Rt

Background

Mouse C3 is a central and essential component of the complement system, acting as the pivotal convergence point for all three complement activation pathways: classical, lectin, and alternative. This ~186 kDa protein, primarily synthesized in the liver, is proteolytically cleaved into two key fragments upon activation: the anaphylatoxin C3a, which recruits and activates immune cells, and the opsonin C3b, which tags pathogens for phagocytosis and amplifies the complement cascade. Its critical roles include mediating innate immune defense against infections, clearing immune complexes and apoptotic cells, and bridging innate and adaptive immunity. Consequently, Mouse C3 is a major focus of research in infectious disease, autoimmunity (e.g., lupus), neuroinflammation, and ischemia-reperfusion injury, with genetically modified C3-deficient mice being a fundamental tool for elucidating its precise functions in vivo.

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SKU: 125030485

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4.9 ★★★★★
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L
Verified Purchase
Linda Hamilton
Cuba, US
★★★★★ 4
Excellent durability but one safety hazard the squeakers comes out.
Style: Bone
Well made for chewing except the squeekers on each end can come out and choke the dog, my dog was chewing on the end of it, and the squeaker came out. I picked it up before he could swallow it. They are choking hazards. That’s the only part that was bad about the product. It’s very sturdy for my little puppy. He uses his mollars. He really gets down to business when he’s chewing 😂
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 22, 2026
P
Verified Purchase
P Nacario
West Palm Beach, US
★★★★★ 5
Great chew toy!
Style: Bone
My dogs love it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 6, 2026
J
Verified Purchase
Julie
Waukegan, US
★★★★★ 5
Baby shark hasn’t destroyed it
Style: Bone
Great for puppy’s that chew up toys. Very durable so far.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 5, 2026
W
Verified Purchase
Whitljc
Boise, US
★★★★★ 1
NOT for aggressive chewers
Style: Bone, Style: Bone
This toy is not for aggressive chewers. I wish I would have looked at the reviews first. Our GSP chewed the end of the toy off within 5 minutes.
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Reviewed in the United States on December 4, 2025
A
Verified Purchase
Amazon Customer
San Leandro, US
★★★★★ 5
Dog toy
Style: Bone
My dog loves this toy. As a matter of fact it is box favorite. I can't believe how long it has lasted him. He typically chews up and breaks his toys fast, not this one 😊
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Reviewed in the United States on April 16, 2026

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