SKU: 13670575914

UniOne® TR-FRET Human IL17A/IL17RA Binding Kit

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Description

UniOne® TR-FRET Human IL17A/IL17RA Binding KitProduct Specification Host Human Stability & Storage 80 Background This kit uses Homogeneous Time Resolved Fluorescence(TR FRET) technology to measure the interaction between IL17A and IL17RA. Thismethod enables simple and rapid high throughput screening of inhibitors andantibody blockers. As shown in the figure, the interaction between IL17A andIL17RA is detected using an Eu labeled anti Tag1 antibody (TR FRET donor) andan Acceptor labeled IL17A

Product Specification


Host Human
Stability & Storage

-80℃

Background

This kit uses Homogeneous Time-Resolved Fluorescence(TR-FRET) technology to measure the interaction between IL17A and IL17RA. Thismethod enables simple and rapid high-throughput screening of inhibitors andantibody blockers.

As shown in the figure, the interaction between IL17A andIL17RA is detected using an Eu-labeled anti-Tag1 antibody (TR-FRET donor) andan Acceptor-labeled IL17A protein (TR-FRET acceptor). The binding of IL17A toIL17RA brings the donor antibody and the acceptor-labeled protein into closeproximity. Excitation of the donor antibody then triggers FluorescenceResonance Energy Transfer (FRET) to the acceptor, resulting in the emission ofa specific signal at 665 nm. The intensity of this specific signal isproportional to the extent of the IL17A/IL17RA interaction. This homogeneousassay is simple to perform and requires no washing steps.



Components

Table 1. Reagents and Storage Conditions

Component

Concentration

100 TESTS

500 TESTS

2500 TESTS

10000 TESTS

Storage Temperature

IL17A-01A protein

100×

5μL

25μL

125μL

500μL

-80°C

Tag1- IL17 RA protein

100×

8μL

40μL

200μL

800μL

-80°C

Anti-Tag1 Eu dye antibody

50×

10μL

50μL

250μL

1000μL

-80°C

Detection buffer

10×

400μL

2mL

10mL

40mL

-80°C

*Reagents should be protected from repeated freeze-thaw cycles. Aliquot upon first thaw and store according to the recommended conditions. The shelf life is one year.

Shipping Notes
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Exchange/Return Notes
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SKU: 13670575914

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4.8 ★★★★★
Based on 22 reviews
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Product Reviews
D
Verified Purchase
Doc
Port Orchard, US
★★★★★ 5
Great Toy for tiny to giant pups
Color: Gray, Size: 8 IN
Cute Amarillo. My teacup Yorkie uses it as a pillow or chases and attacks it. Well stretched does not easily fall apart. Good value for the money. Suitable for all sized dogs.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 3, 2026
J
Verified Purchase
James Brummett
Houston, US
★★★★★ 4
Fun dog toy, but not for heavy chewers
Color: Pink, Size: 14 IN
The armadillo is cute. My pittie, Sasha, was very excited to see it. She just had TPLO surgery on her left knee (she tore her ACL just before the 4th of July), and I wanted to get her something she could play with while she convalesces, that isn't a ball—she really likes to run and jump and chase the ball, but with her knee out of commission, I didn't want her to get depressed being trapped in her crate while she heals—with this toy, she was able to keep playing and not over excert herself and get more hurt. It quickly became her favorite toy; she chews it relentlessly and gets made when I take it from her (see below). It makes a funky squeak that's not a high-pitched squeak, like I thought it would be; it's more a low-pitched, lowing sound like a baby calf. One thing I would like to point out to other purchasers about what the description says: "Durable and Long Lasting - Made from premium soft materials, our cute plush dog toys can withstand rough play for indoor or outdoor and last for years to come. The textured surface also helps massage and soothe your dog's gums during playtime" This is a little misleading. It's a good texture and Sasha loved to play with it, but it wasn't very durable. It might be when compared to other chew toys, but not for my baby. She tore the nose off within 20 minutes of getting it. The next morning, she ripped off an ear, and I had to pull the stuffing out of the face so she wouldn't eat it while chewing away. She doesn't seem to mind, but I sure wish it had held up a little more. All-in-all, this was a good toy for a few days.
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Reviewed in the United States on July 29, 2025
M
Verified Purchase
Maria
Massapequa, US
★★★★★ 5
Cute durable dog toy that my puppy loves
Color: Blue, Size: 8 IN
This small light weight dog toy is very durable, super cute, and my dog loves it. My dog tears everything up but he hasn't made a dent in this; very durable and chew resistant. He seems to really like that it makes a lower squeak noise. I threw this in my cart at the last minute before checkout and I am pleasantly surprised with the quality. I would say this toy is worth the price; suitable for small to medium sized dog.
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Reviewed in the United States on June 2, 2026
I
Verified Purchase
IntelliCABlonde
Lexington, US
★★★★★ 5
Nice toy for a bigger dog
Color: Gray, Size: 6 IN
My little rescue chihuahua has exactly one toy he can make squeak. This one is cute and he did try, but no luck. I have two large baskets of toys I've bought in the 3 years I've had him. He is only able to make one squeak. He loves it to death because he loves the squeak. It's a hedgehog that I will try to find on Amazon and replace. Poor little dog just has a very small mouth.
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Reviewed in the United States on June 3, 2026
A
Verified Purchase
Al
Lexington, US
★★★★★ 5
Semi durable
Color: Gray, Size: 8 IN
My dog has had this for 1 month, and it is still doing good! It has lost 3 out of 4 legs, but thw body is pretty strong. Dog loves the honk noises.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 7, 2026

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