Mouse Anti-Human CD268 (BAFF Receptor) Antibody (S-4520)
SKU: 14107086715

Mouse Anti-Human CD268 (BAFF Receptor) Antibody (S-4520)

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Description

Mouse Anti-Human CD268 (BAFF Receptor) Antibody (S-4520)Product Specification Host Mouse Antigen CD268 (BAFF Receptor) Synonyms Tumor necrosis factor receptor superfamily member 13C; B cell activating factor receptor; BAFF receptor (BAFF R); BLyS receptor 3; BAFFR; BR3; TNFRSF13C Location Membrane Accession Q96RJ3 Clone Number S 4520 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical

Product Specification


Host Mouse
Antigen CD268 (BAFF Receptor)
Synonyms Tumor necrosis factor receptor superfamily member 13C; B-cell-activating factor receptor; BAFF receptor (BAFF-R); BLyS receptor 3; BAFFR; BR3; TNFRSF13C
Location Membrane
Accession Q96RJ3
Clone Number S-4520
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Hu

Background

CD268, also known as the B-cell Activating Factor Receptor (BAFF-R or BR3), is a type III transmembrane protein belonging to the tumor necrosis factor receptor (TNFR) superfamily that plays a pivotal role in B lymphocyte biology by serving as the primary high-affinity receptor for BAFF (BLyS). Predominantly expressed on the surface of mature and transitional B cells, CD268 is essential for B cell survival, maturation from the transitional to the follicular stage, and the maintenance of peripheral B cell homeostasis through the activation of key signaling pathways such as NF-κB (both canonical and non-canonical), PI3K/Akt, and MAPK. Upon binding to its ligand BAFF, CD268 prevents apoptosis by upregulating anti-apoptotic proteins like Bcl-2 and Mcl-1, thereby ensuring the longevity of the B cell pool; conversely, defects or deficiencies in CD268 signaling lead to a severe reduction in mature B cell numbers and impaired humoral immunity. Due to its critical function in B cell survival, CD268 is a significant therapeutic target in autoimmune diseases characterized by B cell hyperactivity, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis, as well as in B cell malignancies, where blocking this receptor can effectively induce the depletion of pathogenic or malignant B cells.

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SKU: 14107086715

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4.2 ★★★★★
Based on 1537 reviews
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Abbi
Lexington, US
★★★★★ 4
4/5 Stars
Size: 4 Panel-88'', Color: Black
Very tall and easy to set up, the only thing I will say is that they do have large gaps in between, so you won't have 100% privacy unless you add a curtain in the back. Other than that, they are easy to fold, sturdy, and esy to assemble. The gaps are an easy fix so I would say they are worth it.
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Reviewed in the United States on April 16, 2026
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Tyi Campbell
Lowell, US
★★★★★ 5
Great product and worth the money.
Size: 4 Panel-88'', Color: Black
Portable and stable. Perfect size and gives me the privacy I need when working from home. Stability is great as long as you place the stands correctly it won't wobble. I love it.
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Reviewed in the United States on May 8, 2026
M
Verified Purchase
Mona T.
Dallas, US
★★★★★ 5
Attractive
Size: 4 Panel-88'', Color: Grey
The assembled product is just as described. The screens look great! I am using them to hide the cluttered shelving in my garage. The area now looks quite neat Something I must say, though, is that the assembly was extremely difficult. I had to use a silicone spray and some pounding to get the A and B poles to fit together. Also, it required a great deal of strength to stretch and hold the fabric panels so that the bars inserted in each hem lines up with the screws inserted in A/B poles. I strongly recommend having a partner to help with the assembly. while sc and screw into poles them once inserted intetchedtne end of each pole ( and B poles barely fit together. I used silicone spray on the end and then pounded them
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Reviewed in the United States on December 12, 2025
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Verified Purchase
karine
Charlottesville, US
★★★★★ 5
Works
Size: 3 Panel-102'', Color: Beige, Size: 3 Panel-102'', Color: Beige
It’s beige and not white. Once install - hard to disinstall. Need a drill to put it together
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Reviewed in the United States on May 4, 2026
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ralversity
Lexington, US
★★★★★ 3
Does the job, but assembling by yourself is a nightmare
Size: 4 Panel-88'', Color: Black
Does it do the job? Yes, although as others said there are small gaps but it's not a huge deal. The price is also good. But the reason I'm giving it a 3/5 is simply because the assembly for this was a complete nightmare. I honestly don't think I would recommend this to anyone unless they have another person to help them assemble it, because doing it by myself was terrible. I don't think I'd buy this again, I think I'd opt to just spend a bit more money and save myself the trouble personally.
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Reviewed in the United States on May 29, 2026

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