SKU: 14263026824

Galectin-9 His Tag Protein, Human

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Description

Galectin-9 His Tag Protein, HumanProduct Specification Species Human Antigen Galectin 9 Synonyms Gal 9, Ecalectin, Tumor antigen HOM HD 21 Accession O00182 2 Amino Acid Sequence Ala2 Thr323, with N terminal 8* His

Product Specification


Species Human
Antigen Galectin-9
Synonyms Gal-9, Ecalectin, Tumor antigen HOM-HD-21
Accession O00182-2
Amino Acid Sequence

Ala2-Thr323, with N-terminal 8* His

HHHHHHHHAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT

Expression System HEK293
Molecular Weight

47-55kDa (Reducing)

Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Iwasaki-Hozumi H., Chagan-Yasutan H., Ashino Y., Hattori T. Blood Levelsof Galectin-9, an Immuno-Regulating Molecule, Reflect the Severity for theAcute and Chronic Infectious Diseases. Biomolecules. 2021;11:430.

2.Nishi N., Itoh A., Fujiyama A., Yoshida N., Araya S.-i., Hirashima M.,Shoji H., Nakamura T. Development of highly stable galectins: Truncation of thelinker peptide confers protease-resistance on tandem-repeat type galectins.FEBS Lett. 2005;579:2058–2064.

3.Oomizu S., Arikawa T., Niki T., Kadowaki T., Ueno M., Nishi N., Yamauchi A., HirashimaM. Galectin-9 suppresses Th17 cell development in an IL-2-dependent butTim-3-independent manner. Clin. Immunol. 2012;143:51–58. d

4.Bozorgmehr N., Mashhouri S., Perez Rosero E., Xu L., Shahbaz S., Sligl W.,Osman M., Kutsogiannis D.J., MacIntyre E., O’Neil C.R., et al. Galectin-9, aPlayer in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker inSARS-CoV-2 Infection. mBio. 2021;12:e00384-21.


Background

Galectin-9 is a β-galactoside binding lectin known for its immunomodulatory role in various microbial infections. Gal-9 is expressed in all organ systems and localized in the nucleus, cell surface, cytoplasm and the extracellular matrix. Gal-9 structurally consists of two homologous carbohydrate-recognition domains at the N- and C-terminus (NCRD and CCRD, respectively) linked by a linker peptide that is highly susceptible to proteolysis. It mediates host-pathogen interactions and regulates cell signalling via binding to its receptors. Gal-9 is involved in many physiological functions such as cell growth, differentiation, adhesion, communication and death. Gal-9 is a molecule that positively and negatively adjusts immune systems as both a contributing factor in cytokine storm and an immunosuppressive molecule inducing, for instance, T-cell exhaustion and apoptosis.


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SKU: 14263026824

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Richard H Harrison
Lake Worth, US
★★★★★ 5
Great toy to play fetch with the dogs.
Color: Black/White, Size: Large
These balls are a great dog toy to play fetch with your dogs. This not the first ball I have gotten for the dogs. Just the right size and weight for medium sized dogs. I have less concerns about them possibly choking on these soccer balls versus tennis balls. So I can leave them out for them to play with. The are easy to inflate using the included pump. My only concern is the durability of the straps as my dogs have almost torn off one the straps of the previous ball I purchased.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 2, 2026
K
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Kendall
Birmingham, US
★★★★★ 5
Dog parents; buy this now!
Color: Black/White, Size: Medium
A must have for my pup! I have bought this at least 5 times. She eventually pops them and I need a new one. It's an amazing toy that she can thrash and we can play fetch with
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Reviewed in the United States on May 1, 2026
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Verified Purchase
Tricia Rees
Boise, US
★★★★★ 5
Westie LOVES this toy
Color: U.S.A, Size: Medium
My pup (Westie) adores this toy. This is actually our second one. The ball itself is resistant but the straps will be obliterated. Would definitely recommend! Totally worth the price!
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Reviewed in the United States on May 11, 2026
R
Verified Purchase
regina
San Leandro, US
★★★★★ 3
Not durable
Color: Black/White, Size: Large
If you have a dog who likes to pop things then this toy isn't it. Within 5 min she had this ball popped. It was made to sound like it was durable for this type of thing but it definitely is not so just be aware. Now if you have a dog who doesn't pop things easy then this would be a good toy
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Reviewed in the United States on May 15, 2026
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Verified Purchase
Billie W
Phoenix, US
★★★★★ 5
They last quite well, even out in weather.
Color: Black/White, Size: Medium
NY corgi loves these!
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Reviewed in the United States on May 31, 2026

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