SKU: 15182109649

Invivo anti-Mouse CD119 Recombinant mAb

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Description

Invivo anti-Mouse CD119 Recombinant mAbProduct Specification Host Rat Antigen CD119 Synonyms Interferon gamma receptor 1; IFN gamma receptor 1; IFN gamma R1; Interferon gamma receptor alpha chain (IFN gamma R alpha); Ifngr; Ifngr1 Location Cell membrane Accession P15261 Clone Number S 3783 Antibody Type Rat mAb Isotype Rat IgG2a,k Application FCM, In vitro IFNR neutralization, In vivo IFNR neutralization Reactivity Ms Purification Protein G Concentration 5 mg ml Purity >95%(Determined by

Product Specification


Host Rat
Antigen CD119
Synonyms Interferon gamma receptor 1; IFN-gamma receptor 1; IFN-gamma-R1; Interferon gamma receptor alpha-chain (IFN-gamma-R-alpha); Ifngr; Ifngr1
Location Cell membrane
Accession P15261
Clone Number S-3783
Antibody Type Rat mAb
Isotype Rat IgG2a,k
Application FCM, In vitro IFNγR neutralization, In vivo IFNγR neutralization
Reactivity Ms
Purification Protein G
Concentration 5 mg/ml
Purity >95%(Determined by SDS-PAGE)
Endotoxin <1EU/mg
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, containing no preservative
Stability & Storage

2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.

Background

CD119, also termed IFN-γ receptor 1 (IFNGR1), is a 54 kDa type-II cytokine receptor that forms, together with IFNGR2, the high-affinity heterotetrameric receptor for interferon-γ; upon IFN-γ binding it recruits JAK1 and JAK2 to phosphorylate STAT1, thereby driving transcription of antiviral, antigen-presentation and pro-inflammatory genes that activate macrophages, enhance Th1 responses and enforce host defence against intracellular pathogens, while inherited mutations in CD119 cause Mendelian susceptibility to mycobacterial disease.

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Exchange/Return Notes
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SKU: 15182109649

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4.6 ★★★★★
Based on 6 reviews
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Product Reviews
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Verified Purchase
fenglinyang
Alexandria, US
★★★★★ 5
Great chair for everyday use
I’m really happy with this ergonomic chair. It was easy to put together and feels very sturdy once assembled. The mesh back is breathable and keeps my back cool even after sitting for hours. The seat cushion is comfortable and supportive, and the armrests are positioned well for working at a desk. I also like how smoothly the wheels roll and how easy it is to adjust the height. For the price, the quality is honestly better than I expected. I’ve been using it every day for work and it makes long sitting sessions much more comfortable. Definitely a great value and I would recommend it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 10, 2026
A
Verified Purchase
Amazon Reviews
Birmingham, US
★★★★★ 5
Excellent quality, comfortable for 8+ hour days
Color: Grey, Color: Grey
Since the reviews here were so very helpful to me, I decided to leave my own after using this chair a couple days. To summarize: Overall, I am thrilled with this chair and would recommend! I work remote, in a small apartment and this works well for both space saving and silence when rolling over hardwood floors all day. For more details, read on! It came packaged very nicely, so everything was well protected during shipping. There are no written instructions and to be honest, I didn't even look for them. If you've put one together before, this is pretty standard. The "leather" (not genuine, but feels like it) is thick and seems it will be sturdy for a long time. The padding is exceptional and that's the main reason I needed a new chair, as mine (a 'basic' brand one, IYKYK) only lasted one year before it felt like sitting on a hard plastic seat. The height is adjustable to go up higher than most, so for once I didn't have to raise it all the way to feel comfy. The surprisingly great thing about it is the arms that flip up, so I can push it all the way under my desk. I live in a small apartment, so every bit of space saved is a bonus! Speaking of apartments, the wheels on this are whisper quiet and I'm more than certain the neighbor below me is thrilled to not hear my clunky wheels from the other chair anymore. I was hesitant to pay too much for an office chair, but given the price and the quality, I feel it was an excellent purchase. A few items to note, if you have never put one together before: hand tighten the screws first! Don't put them on full force, until the pieces have been mostly assembled. This will help it not come out lopsided and the holes will be a little easier to line up. Watch the video, it will make the process a little easier (unlike what I did - put the arms on correctly, thought that looked wrong, then put them on backwards and lost my mind LOL). The video will also show how to recline the chair, if you like that (I do). It has a recline that's smooth as butter.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 11, 2026
J
Verified Purchase
Julia
Grantham, US
★★★★★ 5
Very comfortable and safe chair
This executive desk chair is very convenient , for its 90° flip-up armrests can be easily pushed under the desk, perfect for home office. The rubber wheels roll smoothly and quietly on my carpet. It supports up to 275 pounds so it is safe to me . The height-adjustable back with 360° swivel makes me move freely . The curved, padded backrest provides relieve back pressure , also it is very easy to set up.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 22, 2026
L
Verified Purchase
Lory Johnson
Lowell, US
★★★★★ 4
Recommend it for all.
Color: Grey, Color: Grey
Very nice chair. One warning…it went together very easily except for the last screw!!! I finally gave up. A neighbor came over and gave up. My daughter came. Over and after much groaning and moaning got that last screw in.
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Reviewed in the United States on March 17, 2026
D
Verified Purchase
Daniel Ivan
San Leandro, US
★★★★★ 5
Great for home office
Color: Grey, Color: Grey
This was a great replacement to the chair I use when I work from home, padding is firm and comfortable so I have no issue sitting on it for hours, the arm rest are foldable so is very convenient when my dogs are in co worker duty. Very easy to put together and it feels very firm and stable.
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Reviewed in the United States on April 15, 2026

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