SKU: 2049180702

ZONESUN ZS-AFC9H Monoblock Automatic Vial Filling and Half Stoppering Machine With Laminar Flow Hood For Lyophilized Products

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Description

ZONESUN ZS-AFC9H Monoblock Automatic Vial Filling and Half Stoppering Machine With Laminar Flow Hood For Lyophilized ProductsZONESUN vial filling and stoppering machine is designed for precise liquid dosing and flexible vial processing in pharmaceutical, biotech, and related industries. Equipped with a servo driven peristaltic pump, it ensures 1% accuracy while allowing easy tubing replacement for improved cleanliness. The double head filling system delivers 24003600 BPH and can be customized for higher capacity. It supports both half and full stoppering, making it suitable

ZONESUN vial filling and stoppering machine is designed for precise liquid dosing and flexible vial processing in pharmaceutical, biotech, and related industries. Equipped with a servo-driven peristaltic pump, it ensures ±1% accuracy while allowing easy tubing replacement for improved cleanliness. The double-head filling system delivers 2400–3600 BPH and can be customized for higher capacity. It supports both half and full stoppering, making it suitable for lyophilization workflows and integration with crimping machines. Featuring automatic vial feeding, laminar flow protection, GMP-oriented design, and synchronized cam-driven operation, the machine offers efficient, hygienic, and scalable production performance.

Vial Filling and Stoppering Machine Parameter

  • Machine Model: ZS-AFC9H
  • Voltage: AC 110/220 V 50-60 Hz
  • Power: <3000 W/h
  • Working Speed: About 40-60 Bottles/min (Depending on filling range)
  • Filling Pump: Peristaltic Pump
  • Filling Nozzle Quantity: 2
  • Filling Range: Customizable
  • Filling Accuracy: ±3%
  • Package Size: About 610*1900*1270 mm (Laminar Flow Hood) About 2110*1320*2110 mm (Main Machine)
  • Package Weight: About 181 kg (Laminar Flow Hood)+908 kg (Main Machine)

*Specifications are for reference only and may vary by your product. Please confirm with us if required.

 Details of Vial Filling and Stoppering Machine

01. Touchscreen Control Panel

User-friendly interface of the vial filling and stoppering machine for precise parameter adjustment and real-time process monitoring, improving operational efficiency and control.

02. Bottle Sorting System

Automatically aligns and feeds vials into the filling station of the vial filling and stoppering machine. Customizable to accommodate different vial sizes for flexible production.

03. Integrated Cam-Driven Structure

Synchronized multi-station operation ensures stable performance, higher efficiency, and reduced mechanical complexity within the vial filling and stoppering machine.

04. Peristaltic Pump Filling System

Enables hygienic, contamination-free filling in the vial filling and stoppering machine, as liquid only contacts the tubing—ideal for sterile and sensitive pharmaceutical products.

05. Vibratory Bowl Stopper Sorter

Efficiently orients and feeds stoppers for continuous, automated production with minimal manual intervention in the vial filling and stoppering machine.

06. Laminar Flow Hood

Provides a consistent stream of clean air over critical processing areas of the vial filling and stoppering machine, minimizing contamination risks and supporting aseptic-oriented production standards.

07. Protective Dust Cover

Helps isolate the working area of the vial filling and stoppering machine from external particles, enhancing overall cleanliness and product safety.

FAQ of Vial Filling and Stoppering Machine

1. What is the production capacity of this vial filling and stoppering machine?
The machine is equipped with a dual-head filling system, with a typical output of 2400–3600 bottles per hour. The number of filling heads can be customized to meet higher production requirements.

2. Can this machine be used for lyophilization processes?
Yes. The machine supports both half stoppering and full stoppering modes. Half stoppering is suitable for freeze-drying applications, while full stoppering can be used for direct sealing with a crimping machine.

3. How does the machine ensure filling accuracy?
The system uses a servo-controlled peristaltic pump, achieving filling accuracy of up to ±1%. Accuracy may vary slightly depending on liquid properties and tubing conditions.

4. Is this vial filling and stoppering machine suitable for different vial sizes?
Yes. The machine can accommodate multiple vial sizes by changing format parts such as the star wheel and vibratory bowl. This allows it to handle different bottle dimensions and stopper sizes, providing flexibility for various production requirements.

5. Is the filling system easy to clean and maintain?
Yes. The peristaltic pump uses replaceable tubing, which prevents direct contact between the pump and the liquid, making it easy to clean and suitable for applications requiring higher hygiene standards.

6.Is the machine suitable for sterile or cleanroom environments?
The machine is designed with GMP-oriented structure, SUS304 contact parts, and can be equipped with a laminar flow hood to help minimize contamination risk during filling.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 2049180702

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4.5 ★★★★★
Based on 27 reviews
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Product Reviews
A
Verified Purchase
Albacore Shuffle
Carnegie, US
★★★★★ 5
Very bright !
Size: 2Pcs 7.6Inch Light Bar, Size: 2Pcs 7.6Inch Light Bar
I haven't had a chance to use them on the river yet. I just finished installing them. They were easy to install and they are very bright ! My home is at the end of a cul-de-sac and with my boat parked in the garage I can light up the house on the other side of the street. I'll need to adjust the lights when I'm on the river. The mounting hardware supplied seems like it will be an easy task.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 9, 2023
A
Verified Purchase
Amazon Customer
Louisville, US
★★★★★ 5
Straightforward setup Excellent Warm sound
Style: AVR-S770H
Setup was surprisingly easy. No manual included, but a quick link to a PDF. Connection to PC, Nintendo Switch, Cable Box done in minutes. Setup Menu worked great. Bluetooth pairing to phone easy. Setup as 5.1 (waiting on 2 more speakers for 7.1 connection). Small glitch in that the speakers didn't respond or even test tone right away. Went in and out of menu a few times, and then they worked (did this once with a 2-speaker quicker setup and then did the same glitch when adding the additional speakers to the profile with the full 5.1 setup). Works with ARC well (Samsung TV that came with silly external box) and reciever connection defaults to a passthrough when not on, which is nice. Video is great and compressed audio cleanup works well. Didn't do Mic leveling yet, but the manual speaker tuning worked well at leveling things out for 5.1. I was expected a lot harder set-up and was pleasantly surprised. It's a quality product. Some folks may not like the direct DB volume adjustment but I find it handy, especially when working a little later at night, I can dial in a very exacting low volume so as not to disturb the rest of the house. Very happy with purchase.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 28, 2024
G
Verified Purchase
GMTTD
Fort Morgan, US
★★★★★ 5
Great product
Style: AVR-S770H
I have owned several $1000.00 plus theater systems of 7.1(2) channels and I have never heard my speakers put out the sound like the Denon does. I would never change systems again unless Denon stops producing this product
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Reviewed in the United States on May 13, 2026
J
Verified Purchase
John E. Holiday
Natrona Heights, US
★★★★★ 5
AVR-S770H - My first AVR and my first Denon - works great with Directv and Fire Stick
Style: AVR-S770H
This review is for the Denon AVR-S770H. I was apprehensive about buying an AVR for my main TV. I've always used a soundbar and was happy with the results. I assumed that adding an AVR would make things finicky and complicated. I'm happy to say, that is not true. This Denon has been fabulous. My requirements for a home theater receiver were/are the following: 1) Ease of use and NO additional remotes to our current set-up (family needs, I'm not a bachelor!) 2) I need the ability to connect 2 zones: the TV room and I have a pair of outdoor speakers on the patio First, as to the remote situation, I use Directv and I use an Amazon Fire Stick 4k. My old set-up was super simple. I picked up the Directv remote and hit Power. That turned on the TV, the Directv box, and the soundbar (since it was connected to the TV ARC port). Simple. If I wanted to change over to the Fire Stick, I simply used the same Directv remote to change the input and then used the Fire Stick remote from there. I'm happy to say the Denon has made things even simpler. Not only does the Directv remote turn on/off the TV, Direct box, and the Denon receiver but now I don't even have to bother switching inputs. If I pick up the Fire Stick remote and hit the Home button, the Denon senses that and immediately switches over. Likewise, if I pick up the Directv remote and hit a button, the Denon will switch back over to Directv. So that is an actual improvement. By the way, in order to get the Directv remote to turn off the Denon, don't worry about trying to program the remote via the Directv menu (I tried all the codes and failed). Instead, go to the Denon setting menu. Choose Setup> Video> HDMI Setup. Change the "Power Off Control" to "Video" or "All". Now the Denon will turn on/off when the TV does (using the Directv remote). My second concern was operating a second set of speakers via Zone 2. That also works perfectly. Now when I step outside to sit on the patio, I simply hit the Zone 2 button on the front of the Denon. I can use my phone to play music via the Denon's built-in Bluetooth. Some users need to be aware: in order to operate Zone 2, the receiver needs to be switched from 7.2 channel to 5.1 + Zone 2. That's perfectly acceptable for me since my TV has only front L & R speakers and a subwoofer. So I'm not even using the full capabilities of the 5.1. If you need 7.2 and a second zone, you need to find a different AVR. In sum, I bought this Denon with some trepidation and thought maybe I'd have to return it. Instead, it does everything I want and then some. Of course, it sounds great too. I'm so glad I switched from the soundbar.
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Reviewed in the United States on May 4, 2025
R
Verified Purchase
Ricus
Los Angeles, US
★★★★★ 5
Wow!
Style: AVR-S770H
I had an Onkyo 5100 for a few years and experienced lots of issues with the UI over HDMI but after many many firmware updates they seemed to have resolved that and it had a great sound. Recently however the receiver started to turn itself on for no reason and I felt that it was a fire hazard. I bought this unit as a replacement and so far it is flawless. I believe that this receiver sounds even better and hopefully more reliable. The Atmos sound is excellent.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 25, 2024

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