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Description
PDGF-BB Protein,MouseProduct Specification Species Mouse Synonyms PDGFBB; PDGF BB Accession AAH53430. 1 Amino Acid Sequence Ser82 Thr190 is expressed with a 6His tag at the C terminus Expression System E. coli Molecular Weight 13. 4 KDa Purity >95% by SDS PAGE Endotoxin <1EU g Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer 0. 2 m filtered solution of 4mM HCl. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is
Product Specification
| Species | Mouse |
| Synonyms | PDGFBB; PDGF-BB |
| Accession | AAH53430.1 |
| Amino Acid Sequence |
Ser82-Thr190 is expressed with a 6His tag at the C-terminus
|
| Expression System | E.coli |
| Molecular Weight | 13.4 KDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 0.2 μm filtered solution of 4mM HCl. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Stability & Storage |
|
Background
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor，it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing.
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