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Description
Glycophorin A Recombinant Rabbit mAb (SDT-3349)Product Specification Host Rabbit Antigen Glycophorin A Synonyms Glycophorin A; MN sialoglycoprotein; PAS 2; Sialoglycoprotein alpha; CD235a; GPA; MNS; GYPA Location Cell membrane Accession P02724 Clone Number SDT 3349 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample K562 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0.
Product Specification
| Host | Rabbit |
| Antigen | Glycophorin A |
| Synonyms | Glycophorin-A; MN sialoglycoprotein; PAS-2; Sialoglycoprotein alpha; CD235a; GPA; MNS; GYPA |
| Location | Cell membrane |
| Accession | P02724 |
| Clone Number | SDT-3349 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Positive Sample | K562 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500-1:1000 | Hu |
| IHC-P | 1:1000 | Hu |
Background
CD235a protein, also known as Glycophorin A, is a major intrinsic membrane protein of human red blood cells and erythroid precursor cells. It is a type I sialoglycoprotein with a molecular weight of around 10 kD, present in the cell membrane as a homodimer. This protein serves as a carrier for the MN blood group antigens. It also plays a crucial role in maintaining the integrity and shape of the erythrocyte membrane by being a part of the ankyrin-1 complex. Additionally, CD235a acts as a receptor for several pathogens, including the influenza virus, Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175), and hepatitis A virus.
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