SKU: 20772954901

FITC Mouse Anti-Rat CD45 Antibody (S-R591)

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Description

FITC Mouse Anti-Rat CD45 Antibody (S-R591)Product Specification Host Mouse Antigen Rat CD45 Synonyms Receptor type tyrosine protein phosphatase C; Leukocyte common antigen (L CA); T200; Ptprc Location Cell membrane Accession P04157 Clone Number S R591 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Rt Positive Sample Lewis Rat splenocytes Purification Protein G Concentration 0. 05mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0.

Product Specification


Host Mouse
Antigen Rat CD45
Synonyms Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen (L-CA); T200; Ptprc
Location Cell membrane
Accession P04157
Clone Number S-R591
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Rt
Positive Sample Lewis Rat splenocytes
Purification Protein G
Concentration 0.05mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Rt

Background

CD45, also known as protein tyrosine phosphatase receptor type C (PTPRC) or leukocyte common antigen, is a transmembrane glycoprotein expressed on nearly all hematopoietic cells and plays a crucial role in the regulation of T and B cell antigen receptor-mediated activation. It is a type 1 transmembrane protein tyrosine phosphatase (PTPase) that is involved in the activation, development, tolerance, and survival of T and B-lymphocytes. CD45 is essential for the initiation of T cell receptor (TCR) signaling and modulates cytokine and chemokine production and signaling. It also negatively regulates monocytic cell differentiation and FLT3 signaling in vivo. The protein is involved in the nuclear apoptosis process and is vital for chromatin condensation and DNA fragmentation. Furthermore, CD45 is implicated in the interaction between T cells and macrophages and has been studied as a therapeutic target for immune diseases, including autoimmunity and organ transplantation. Disruption of the equilibrium between protein tyrosine kinase and phosphatase activity, which includes CD45, can result in immunodeficiency, autoimmunity, or malignancy.

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SKU: 20772954901

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4.4 ★★★★★
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Elizabeth Johnson
Charlottesville, US
★★★★★ 4
Well made and very nice material.
Color: Dark Brown, Size: 10
This is a great suit the quality material and the color is better than expected. The slacks have waist adjustments that help with comfort. Definitely worth the price. I give it 4 stars because it was supposed to be a slim fit but the jacket is really loose and not as form fitting as I expected, however the suit is worth the price. My son loves it ! Color is perfect for him!
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Reviewed in the United States on December 27, 2025
M
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Mayraa
Natrona Heights, US
★★★★★ 1
Returned ...
Color: Dark Brown, Size: 20
I ordered the dark brown suit which my son loved. once I looked closely there seemed to be cat hair on it, it looks like it was washed as well, which caused the material to rise and become damaged.
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Reviewed in the United States on April 15, 2026
M
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Machel Moss
Natrona Heights, US
★★★★★ 5
Highly recommend!
Color: Dark Brown, Size: 16
Perfect fit for my 13 year old! The quality and color of the suit was spot on to the description.
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Reviewed in the United States on May 14, 2026
S
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Swathi Panditi
Phoenix, US
★★★★★ 3
Good but not cloth material
Color: Beige, Size: 8
Suit was good but material was kind of old fashioned. In Pictures cloth looks very different compared to in real. Fitting wise I m satisfied but not cloth material.
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Reviewed in the United States on December 8, 2025
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Amy Johnson
Draper, US
★★★★★ 5
Worth it.
Color: Dark Brown, Size: 10
Adorable. Great quality. Fun little suit.
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Reviewed in the United States on April 7, 2026

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