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Description
Nucleoprotein His tag, HRSVB (Strain 18537)Product Specification Species HRSV Synonyms Nucleoprotein, Protein N, Nucleocapsid protein Accession P24566 Amino Acid Sequence Met1 Leu391, with N terminal 8*His
Product Specification
| Species | HRSV |
| Synonyms | Nucleoprotein, Protein N, Nucleocapsid protein |
| Accession | P24566 |
| Amino Acid Sequence | Met1-Leu391, with N-terminal 8*His MHHHHHHHHMALSKVKLNDTLNKDQLLSSSKYTIQRSTGDNIDTPNYDVQKHLNKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTIKILKDAGYHVKANGVDITTYRQDINGKEMKFEVLTLSSLTSEIQVNIEIESRKSYKKLLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEIKRYKGLIPKDIANSFYEVFEKHPHLIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGSGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTAEELEAIKHQLNPKEDDVEL |
| Expression System | E.coli |
| Molecular Weight | 43kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM PB, 150mM NaCl, 1mM EDTA, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Oliveira A P. et al. (2013) Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells. Virus Res. 177(1): 108-112. 2、Céspedes P F. et al. (2014) Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells. Proc Natl Acad Sci U S A. 111(31): E3214. |
Background
Human Respiratory Syncytial Virus (HRSV) is a negative-sense single-stranded RNA virus that belongs to the Paramyxoviridae family and the Pneumovirinae subfamily, and considered the most important pathogen causing respiratory disease in infants and neonates worldwide. The nucleoprotein of HRSV, a canonical cytosolic protein, is highly conserved among pneumoviruses and interacts with viral RNA, generating a helicoidal nucleocapsid which is responsible for genome and anti-genome resistance to RNase. In addition, the nucleoprotein could be responsible for inhibiting T-cell activation during infection by HRSV, and expressed on the surface of epithelial and dendritic cells, preventing immunological synapse assembly by naïve CD4+ T cells. Therefore, this protein is defined as a major virulence factor that contributes to impairing acquired immunity and enhances susceptibility to reinfection by HRSV.
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4.4 ★★★★★
Based on 8 reviews
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Product Reviews
★★★★★ 3
More red than in picture
Color: Brown
Seems like a lovely bag with great quality, but the color was more red than the picture so I sent it back.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 1, 2025
★★★★★ 5
Real genuine leather!!!
This bag is genuine soft leather !Perfect size !! I swapped out the strap for a matching guitar strap .ILOVE THIS BAG! It came with a key chain too!!!
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Reviewed in the United States on March 28, 2024
★★★★★ 1
Sweet purse
Color: Brown
Not worth the cost
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Reviewed in the United States on August 9, 2025
★★★★★ 5
Amazing and would buy it again.
Absolutely love it. It has plenty of interior room and the quality is great. I would recommend it for moms and for anyone that wants a nice looking purse. I’ve had this purse everywhere and it’s holding up. It’s worth the money and I’m considering getting another.
Love the brown interior and the zippers are smooth. Love the strap sizes, too. I can sling it over my shoulder and go.
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Reviewed in the United States on July 4, 2025
★★★★★ 5
Great value for crossbody purse.
Perfect size, made well, zippers are heavy duty, really love this cross body. Was hoping in could have gotten gold hardware on the black bag.
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Reviewed in the United States on August 24, 2025
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