SKU: 21297003283

Alexa Fluor® 700 Mouse Anti-Human CD45RO Antibody (S-R401)

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Description

Alexa Fluor® 700 Mouse Anti-Human CD45RO Antibody (S-R401)Product Specification Host Mouse Antigen CD45RO Synonyms Receptor type tyrosine protein phosphatase C; Leukocyte common antigen (L CA); T200; CD45; PTPRC Location Cell membrane, Synapse Accession P08575 Clone Number S R401 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &

Product Specification


Host Mouse
Antigen CD45RO
Synonyms Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen (L-CA); T200; CD45; PTPRC
Location Cell membrane, Synapse
Accession P08575
Clone Number S-R401
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 700
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD45RO is a transmembrane protein tyrosine phosphatase with a molecular weight of approximately 180-220 kDa, belonging to a splice variant of the leukocyte common antigen CD45 family. It is generated through alternative splicing of the CD45 gene, lacking the exon-encoded A, B, and C regions, thus possessing the smallest extracellular domain among CD45 isoforms. CD45RO is predominantly expressed on memory T cells (including effector memory T cells and central memory T cells), activated T cells, monocytes, and macrophages, serving as a key surface marker for memory T cells. Its intracellular domain contains two highly conserved protein tyrosine phosphatase domains, which regulate the phosphorylation status of Src family kinases (e.g., Lck and Fyn) and play a crucial role in T-cell receptor (TCR) signaling, modulating T-cell activation, proliferation, and immune responses. CD45RO expression is closely associated with pathological processes such as chronic inflammation, autoimmune diseases, and transplant rejection, and it is also an important indicator for assessing T-cell immune function in HIV infection. Given its dynamic expression levels reflecting immune status, CD45RO holds potential value in immune monitoring and disease diagnosis.

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SKU: 21297003283

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Miles Schumacher
Massapequa, US
★★★★★ 5
Durable yet soft ball that our dog enjoys chewing.
The balls are soft and well received by our puppy. They are pretty durable and he enjoys both chasing after them and teething on them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 27, 2025
G
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Gery Allen
Pawtucket, US
★★★★★ 5
size and quality are excellent
Just the right size for our little dog.
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Reviewed in the United States on December 1, 2025
K
Verified Purchase
Kindle Customer
Fort Morgan, US
★★★★★ 4
Deceptive Advertising
There's a little bit of false advertising going on here unless you thoroughly read the description. There are three balls in the picture, but you are only purchasing two. Always read the whole description before buying!
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Reviewed in the United States on September 22, 2025
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Verified Purchase
JULIE A. WENTE
Phoenix, US
★★★★★ 5
Great for indoor fun!
Dog loves it.
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Reviewed in the United States on March 11, 2026
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Verified Purchase
junebugged
Cuba, US
★★★★★ 1
Not the same rubber.
I just received these today. I already have two of the same size direct from the local pet store. The one thing I liked about them that made me want to buy more - my 13lb dog could chew on them all night and never leave a mark. The red one I received was as expected. The blue one I received was not made out of the same rubber. It was softer. We played catch a few times and it didn’t bounce the same. I looked away for 5 minutes and she had it already starting to shred. Not sure what happened but 1 of the 2 balls I was sent was not up to par, possibly defective.
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Reviewed in the United States on May 23, 2024

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