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Description
Anti-PD-1 Monoclonal Antibody(Nivolumab)Product Specification Host Human Antigen PD 1 Synonyms Programmed cell death protein 1, Protein PD 1, hPD 1, CD279, PDCD1 Accession Q15116 Clone Number S SC016 Antibody Type Recombinant mAb Isotype IgG4,k Application Blocking of PD 1 PD L signaling Functional assays Purification Protein A Concentration 2 mg ml Endotoxin <1EU mg Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, containing no preservative Stability & Storage
Product Specification
| Host | Human |
| Antigen | PD-1 |
| Synonyms | Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1 |
| Accession | Q15116 |
| Clone Number | S-SC016 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG4,k |
| Application | Blocking of PD-1/PD-L signaling Functional assays |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| ELISA | 0.305-5000 ng/ml |
Background
Nivolumab is a type of targeted therapy drug called an immune checkpoint inhibitor (a type of immunotherapy). It is a monoclonal antibody that binds to the protein PD-1 on the surface of immune cells called T cells. It works by keeping cancer cells from suppressing the immune system. This allows the immune system to attack and kill the cancer cells.
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Exchange/Return Notes
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