SKU: 23077459801

Alexa Fluor® 488 Mouse Anti-Mouse CX3CR1 Antibody (S-R597)

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Description

Alexa Fluor® 488 Mouse Anti-Mouse CX3CR1 Antibody (S-R597)Product Specification Host Mouse Antigen CX3CR1 Synonyms CX3C chemokine receptor 1; C X3 C CKR 1; mCX3CR1; Fractalkine receptor Location Cell membrane Accession Q9Z0D9 Clone Number S R597 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300

Product Specification


Host Mouse
Antigen CX3CR1
Synonyms CX3C chemokine receptor 1; C-X3-C CKR-1; mCX3CR1; Fractalkine receptor
Location Cell membrane
Accession Q9Z0D9
Clone Number S-R597
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CX3CR1 is a seven-transmembrane G-protein-coupled receptor expressed on monocytes, macrophages, dendritic cells, microglia and tissue-patrolling lymphocytes that serves as the exclusive receptor for the unique membrane-tethered or soluble chemokine CX3CL1 (fractalkine), thereby orchestrating leukocyte adhesion, chemotaxis and survival during development, homeostasis, viral and bacterial infections, inflammatory diseases such as atherosclerosis and rheumatoid arthritis, neuroinflammatory conditions including Alzheimer’s disease, and tumor progression or metastasis, while also acting as a co-receptor for respiratory syncytial virus entry into airway epithelium and modulating antiviral immunity via IL-10 induction.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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SKU: 23077459801

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4.5 ★★★★★
Based on 29 reviews
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J
Verified Purchase
Jodie Lott
Bozeman, US
★★★★★ 5
Survives agressiveness
Color: Large - Billy the Beast Monster
This toy is absolutely for aggressive chewers,my yorkies usually have their stuffed animals torn apart within a day,been a week and not 1 rip! Very happy with it and worth the money!!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026
J
Verified Purchase
John
Boise, US
★★★★★ 4
Great except for one small flaw
Color: Regular - Beak, Color: Regular - Beak
Our dog likes to get at the juicy innards of every toy we buy him. We tried this one as it promised to be "bullet proof". It lasted about a week which in fairness is 6.5 days longer than most of the toys we buy last. He ripped off the wings which was to be expected and not an issue. It took him another 6 days to finally locate a weak point and break in. It appears that the tag is not made of kevlar but merely sewed on. I guess it would be better if they had just sewed it on top but they made it part of the overall structural integrity. This provided a small area of weakness which our dog located and proceeded to exploit. It's like having the death star but installing a small thermal exhaust port that allows for access to the very core of the station. Makes little sense. Overall I am pleased with the overall sturdiness but in the end this toy had a small design flaw that my dog was able to locate and exploit in his neverending quest to gain access to and eat polyester fiber stuffing
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Reviewed in the United States on March 6, 2026
K
Verified Purchase
Kym Brunner
Cuba, US
★★★★★ 5
STRONG AS A MONSTER (albeit a cute one)
Color: Large - Billy the Beast Monster, Color: Large - Billy the Beast Monster
My aggressive chewer ate the adorable monster's ear off on the first day, but who cares? The body of the monster has been indestructible so far (one week). My 7 month old pup cbews it for a good 10-15 minutes at a time several times per day. Great quality product and outlasting all the other toys I bought (which she destroyed in 10 minutes - even the ones rated "Level 4 toughness" from Walmart. I think it's hilarious in my photo that the monster's expression perfectly shows his disappointment about missing an ear, LOL.
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Reviewed in the United States on June 3, 2026
L
Verified Purchase
Lorene
Alexandria, US
★★★★★ 5
King has met his match.
Color: Large - Billy the Beast Monster
I received my dog's toy this evening when I place the toy on the ground my dog King went crazy. He is a one-year-old Pitbull and love to tackle any toy he believes he can't take down, but Mr King has met his match with this toy. He was using all of his bite force to demolish the toy but the toy actually has worn him out. He ran around my yard for about 30 minutes with the toy in his mouth producing the squeaking sound from the toy as well. Hold up the toy is totally filthy with dirt almost covering the entire green and yellow belly of the toy. I have brought king mini toys in the last couple of months and this is the best toy that holds up to his energy level. I tried to retrieve the toy and place it in his dog house because it is far beyond his bedtime, but he wanted to play catch me if You can with my new toy. This is a great toy for those big energetic dogs that love to take their aggression out on maybe some furniture or perhaps that favorite shoe you do not want them to chew on. I am totally sold on this toy I brought from the seller who placed the items on the Amazon site. I plan on purchasing a another toy from the buyer to keep King energy at a low level if I can. I just checked on my dog and he actually has taken the toy with him inside of his dog house and now the toy is snugged under his left paw. I'm one of those smart owners I'm not going to even try to take it from him tonight but hopefully in the next week I can sneak it from him and it may be perhaps wash it. I did this item AA Plus
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Reviewed in the United States on January 31, 2026
B
Verified Purchase
BBarry
Omaha, US
★★★★★ 3
Cute, but not Maligator-proof!
Color: Small - Towering Timmy Monster, Color: Small - Towering Timmy Monster
Fun toy while it lasts. My Belgian Malinois made quick work of this little guy but still enjoys playing with its carcass. Bite Force* but not taking into account the bite force of a Mali-gator!
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Reviewed in the United States on May 7, 2026

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