SKU: 26005888266

P2ry12 Recombinant Rabbit mAb (SDT-3134-52)

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Description

P2ry12 Recombinant Rabbit mAb (SDT-3134-52)Product Specification Host Rabbit Antigen P2ry12 Synonyms P2Y purinoceptor 12; P2Y12; ADP glucose receptor (ADPG R); P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor (P2Y(ADP)); SP1999; HORK3; P2RY12 Immunogen Synthetic Peptide Location Cell membrane Accession Q9H244 Clone Number SDT 3134 52 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu Purification Protein A Concentration 0. 1 mg ml Conjugation Unconjugated Physical

Product Specification


Host Rabbit
Antigen P2ry12
Synonyms P2Y purinoceptor 12; P2Y12; ADP-glucose receptor (ADPG-R); P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor (P2Y(ADP)); SP1999; HORK3; P2RY12
Immunogen Synthetic Peptide
Location Cell membrane
Accession Q9H244
Clone Number SDT-3134-52
Antibody Type Recombinant mAb
Isotype IgG
Application IHC-P
Reactivity Hu
Purification Protein A
Concentration 0.1 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
IHC-P 1:1000 Hu

Background

P2RY12 (purinergic receptor P2Y, G-protein coupled, 12) is a 22 kDa Gαi-coupled seven-transmembrane receptor that is best known as the primary platelet receptor for ADP, where it triggers Rap1- and αIIbβ3 integrin-dependent aggregation and is the target of widely used antithrombotic drugs such as clopidogrel; beyond hemostasis, the same receptor is expressed on osteoclasts, microglia, vascular smooth-muscle cells and certain neurons, mediating ADP-evoked bone resorption, microglial chemotaxis and synaptic pruning, foam-cell formation in atherosclerosis, and neuroinflammatory responses that can either exacerbate or protect against neurodegeneration depending on context.

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SKU: 26005888266

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4.6 ★★★★★
Based on 27 reviews
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Isaiah O
New York, US
★★★★★ 5
Comfortable, Easy to Clean, and Held Up at Coachella
Size: 12, Color: White, Size: 12, Color: White
I’m really happy with this purchase. The shoes are very comfortable, and the product description is accurate. I followed the sizing recommendation based on my foot type and went one size up—they fit perfectly. I bought these for Coachella, and they definitely held up. I was on my feet all day, and they stayed comfortable the entire time. What impressed me most is how easy they were to keep clean. At the end of each day, I was able to wipe them down and maintain their whiteness without much effort. Once I got home, I gave them a deeper clean, and they honestly looked as good as new. Even the laces cleaned up easily. Now I’ve transitioned them into my regular work shoes, and they still look great. Overall, I’m very satisfied with this purchase and would definitely recommend them.
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Reviewed in the United States on May 4, 2026
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Verified Purchase
Hawaiian
West Palm Beach, US
★★★★★ 4
Great shoes that are well made, lite weight, and comfortable.
Size: 12, Color: Brown
Just received my 2nd pair of shoes from Bruno Marc in a size 12. These are really lite and comfortable. It can be dressed down to be a casual shoe or dressed up with a nice suit. These run true to size so I ordered my usual size 12 and the fit was perfect. Being my 2nd pair of Bruno Marc's, I like the quality of their shoes and each shoe is described appropriately on fit and comfort. Insole of these shoes were awesome and provided soft comfort on the feet along with a slight arch support too. Will definitely consider ordering more Bruno Marc shoes in the future.
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Reviewed in the United States on March 11, 2025
J
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JCMIV63
Pawtucket, US
★★★★★ 5
Cushioned, comfortable, stylish and a rubber sole!
Size: 10, Color: Brown
These shoes check multiple boxes for me, comfortable, cushioned, rubber sole and stylish. As my feet grow old and worn out, I'm on a constant search for comfortable, cushioned shoes that are suitable for work and dressier occasions. I have tried many expensive shoes that look great but either lack cushioning, arch support and or comfort. One of the nice things is these shoes have a rubber sole, where most cushioned shoes have the foam soles which are great, but they tend to lack grip particularly when its damp/wet. They have average arch support, but the insole is removable and I put my own cushioned arch support. Love these!
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Reviewed in the United States on April 6, 2026
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DDD Projects
Natrona Heights, US
★★★★★ 5
OG Style
I am a big fan of Bruno Marc shoes. Over the years they have provided comfortable and affordable boots and shoes. These blue, tan and white soled dress sneakers are no exception. They have a nice finished look that makes them both causal and dressy. The lightweight style is still warm enough for colder mid-west winters. The box of the toes is wide and comfortable. The insole is well padded and a pleasure to wear. This is another fine pair of shoes to add to my collection and yours.
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Reviewed in the United States on January 14, 2026
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Premium Reviews
Pawtucket, US
★★★★★ 5
Must buy: Comfort + Casual + Well Made / Ventilated
Size: 8, Color: Brown
Just buy it! I have put in roughly 15,000 steps in this shoes in 10 days and I can't believe how comfortable they are after this much rough use in short amount of time. I highly recommend this shoes to anyone looking for comfort in casual style.
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Reviewed in the United States on May 4, 2026

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