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Description
CD147 Recombinant Rabbit mAb (SDT-681-18)Product Specification Host Rabbit Synonyms Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer (EMMPRIN), Hepatoma associated antigen, (HAb18G), Leukocyte activation antigen M6, OK blood group antigen, Tumor cell derived collagenase stimulatory factor (TCSF) Immunogen Synthetic Peptide Location Cell membrane Accession P35613 Clone Number SDT 681 18 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P
Product Specification
| Host | Rabbit |
| Synonyms | Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer (EMMPRIN), Hepatoma-associated antigen, (HAb18G), Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor (TCSF) |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P35613 |
| Clone Number | SDT-681-18 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:2000 | |
| IHC-P | 1:500 |
Background
CD147, also known as basigin and extracellular matrix metalloproteinase inducer, is a 38-58 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
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Exchange/Return Notes
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