SKU: 27330338639

GDF3 Recombinant Rabbit mAb (S-3049-3)

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Description

GDF3 Recombinant Rabbit mAb (S-3049-3)Product Specification Host Rabbit Antigen GDF3 Synonyms Growth differentiation factor 3; GDF 3 Immunogen Synthetic Peptide Location Cytoplasm, Secreted Accession Q9NR23 Clone Number S 3049 3 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu, Ms Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage

Product Specification


Host Rabbit
Antigen GDF3
Synonyms Growth/differentiation factor 3; GDF-3
Immunogen Synthetic Peptide
Location Cytoplasm, Secreted
Accession Q9NR23
Clone Number S-3049-3
Antibody Type Recombinant mAb
Isotype IgG
Application IHC-P
Reactivity Hu, Ms
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
IHC-P 1:100-1:250 Hu, Ms

Background

GDF3 (growth differentiation factor 3) is a secreted, cysteine-knot-containing ligand of the TGF-β superfamily that acts as a context-dependent morphogen during early embryogenesis, axial patterning, and cartilage formation by binding specific type I/II receptor serine kinases to activate SMAD2/3 or SMAD1/5/8 signaling cascades, thereby regulating target genes that control cell fate, proliferation, and extracellular-matrix production; pathogenic missense variants (e.g., R84C, R84L, R266C) disrupt its biosynthesis, secretion, or receptor engagement and are strongly linked to congenital skeletal malformations such as Klippel-Feil syndrome and scoliosis, while in adipose tissue its expression is acutely up-regulated by cold exposure, suggesting a newly recognized role in adaptive thermogenesis.

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SKU: 27330338639

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4.3 ★★★★★
Based on 28 reviews
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K
Verified Purchase
Kristen Linscott
Massapequa, US
★★★★★ 4
Omegaverse
Format: Kindle
I was pleasantly surprised by this omega verse book. This 1 definitely had a few new twists And I really enjoyed reading it. The main female character was a badass and awesome. She had 1 best friend I wish we could have seen a little bit more of their friendship in this book. Her relationship with the male characters was good not to contrived or super instantaneous. And we had some fun plot twists that I didn't expect. I wish we had more of a follow up on the situation with her family her background and her mother who was a wench. I would definitely recommend this book.
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Reviewed in the United States on April 9, 2025
A
Verified Purchase
Amanda
Natrona Heights, US
★★★★★ 5
Wow. Just wow. An amazing read
Format: Kindle
This book was eloquently written, or should I say the authors writing style is very eloquent? I loved the characters, and the story was quite compelling. I absolutely loved the FMC, she's a BA who doesn't take any crap & gives as good as she gets. A certain person certainly got his just desserts & then some, the earlier scenes of which were quite satisfying, had me punching the air & everything haha. All in all 20/10, great read
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Reviewed in the United States on November 29, 2024
L
Verified Purchase
Lauren
Boise, US
★★★★★ 3
My opinion
Format: Kindle
Let me preface this by saying I really liked the story and the characters however, this book is in desperate need of some sort of editing. It's not misspelled words or formatting, but continuous run on sentences. Redundancies within the sentences. There were a couple of paragraphs that I had to go back and reread 3 or 4 times. Overall, I'd say it was worth the read.
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Reviewed in the United States on May 29, 2025
A
Verified Purchase
Amazon Customer
Pawtucket, US
★★★★★ 5
Beautiful
Format: Kindle
I love omegaverses I had looked at this one multiple times thinking it's just another book about cocky rock star guys that let fame get to their heads and there are parts like that so I wasn't 100% off. I started reading the second book and met the fmc Astraea from the first one,after she had a run in with the aphla from the gym.😁 it gave me the push to stop and read book one first and im so glad I did this book was amazing their was so many characters I fell in love with hoping they will find their happily ever after. the guys were great, the plot was 🎯, and the ending had me 😭😭😭. I was wondering how nate could ever redeem himself, and he did. the last scene with him was sad, but I also felt it was beautiful. thank you to the author for making a beautiful omegaverse book that gave me all the feels. now I'm jumping straight into book two.
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Reviewed in the United States on March 25, 2025
E
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E
West Palm Beach, US
★★★★★ 4
Knot their Omega
Format: Kindle
It took me a day to really get into the book, there is a lot happening in the beginning of the story. I wish there was more of a time frame because I felt like something’s happened quickly but they were farther away than I thought so that was a little confusing to me. I felt like there was so much happening but also not enough. As for the story itself I enjoyed it, it was different than other OV I’ve read. Bring the tissues, you will need them. They guys were great, I wish we saw more of Kai and Kenjis relationship. As for Nate…… IYKYK. I enjoyed this book, my first from this author and look forward to reading about Kamaris story. Book: ⭐️⭐️⭐️⭐️/5 Spice: 🌶️.5/5
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Reviewed in the United States on October 24, 2024

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