SKU: 28374225317

Human Kim-1 , His tag

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Description

Human Kim-1 , His tagProduct Specification Species Human Synonyms Kidney injury molecule 1, T cell immunoglobulin and mucin domain containing protein 1 (TIMD 1), T cell immunoglobulin mucin receptor 1 (TIM; TIM 1), T cell membrane protein 1, CD365, HAVCR1 Accession Q96D42 Amino Acid Sequence Protein sequence(Q96D42, Ser21 Gly295, with C 10*His)

Product Specification


Species Human
Synonyms Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1), T-cell immunoglobulin mucin receptor 1 (TIM; TIM-1), T-cell membrane protein 1, CD365, HAVCR1
Accession Q96D42
Amino Acid Sequence

Protein sequence(Q96D42, Ser21-Gly295, with C-10*His) SVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGGGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight Theoretical:31.1kDa Actual: 39, 75-110kDa
Purity

>95% by SDS-PAGE

Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

KIM-1 (Kidney Injury Molecule -1) is a protein the most highly upregulated in injured kidneys by various types of insults. Its upregulation during renal injury has been found in the kidneys of the vertebrates such as Zebrafish and humans. A soluble form of human KIM-1 can be detected in the urine of patients with ATN and may serve as a useful biomarker for renal proximal tubule injury facilitating the early diagnosis of the disease and serving as a diagnostic discriminator.

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SKU: 28374225317

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4.1 ★★★★★
Based on 28 reviews
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Rob Tilka
Charlottesville, US
★★★★★ 4
Just have to be careful not to take more than one per night or else wake up feeling like have a hangover
Size: 200 Count (Pack of 1)
Definitely works for me. Just have to be careful not to take more than one per night or else wake up feeling like have a hangover. Works great for me but not as well for my stepmother. She has severe insomnia and has been on sleeping medications for years. She tried taking this to go a more natural route but did not even affect her.
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Reviewed in the United States on January 9, 2018
P
Verified Purchase
Patricia Dodd
West Palm Beach, US
★★★★★ 5
surprised!
I actually didn't realize I had ordered "time released" version. I thought these were just normal melatonin. But now that I've tried these, I love them so much better than the regular version! Helps me sleep better through the night. No taste, love this brand of Source Naturals.
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Reviewed in the United States on October 17, 2025
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ChelaTho813
Belleville, US
★★★★★ 5
The only one I'll use!
As the title says, this is the brand to get!! It's fast-acting, doesn't give me weird dreams like some do, and I never wake up feeling groggy.
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Reviewed in the United States on March 13, 2025
B
Verified Purchase
Belle of the Ball
Whiting, US
★★★★★ 5
Works wonders
I've been buying these for well over a year now as Subscribe and Save. I work 12 hour overnights as a nurse. My sleep schedule normally gets messed up. I would have no problem falling asleep but would wake up only a few hours later which is not good when you have work again that night. We buy these on Amazon due to the great price and the fact that they are extended release which helps keep me asleep longer. When I take 1 or 2 of them, I am able to sleep about 7-8 hours which is great. I take this both when I sleep during the day and sleep during the night. It helps me sleep no matter when and I am able to adjust my sleep schedule often. I have recommended them to many.
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Reviewed in the United States on January 10, 2013
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Verified Purchase
PSBone
Waukegan, US
★★★★★ 4
Works quite well, dose still a bit high for me
Used to take the Natrol 5mg slow release, now that I can compare these 2, I love this more. It doesn't make me feel too edgy, it's quite relaxing actually. I still have to halve the dose as the full dose makes me groggy the next day. Where the Natrol gave me very vivid, but not unpleasant dreams, these don't make me dream as vividly. It does take a bit longer to get me to sleep, but once asleep, your asleep. Highly recommend, once I finish this bottle, I'd get the 2mg tr next time, as a lower dose works better for me.
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Reviewed in the United States on July 10, 2014

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