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Description
IL-4 Protein, HumanProduct Specification Species Human Synonyms IL4; IL 4; interleukin 4; MGC79402; pitrakinra; B cell growth factor 1; BCDF; BCGF1; BCGF 1; binetrakin; BSF1; BSF 1; BSF 1 Accession P05112 1 Amino Acid Sequence His25 Ser153 Expression System HEK293 Molecular Weight The protein has a predicted MW of 14. 96 kDa. Due to glycosylation, the protein migrates to 23 25 kDa based on Bis Tris PAGE result. Purity > 95% as determined by Bis Tris PAGE& HPLC Endotoxin
Product Specification
| Species | Human |
| Synonyms | IL4; IL-4; interleukin 4; MGC79402; pitrakinra; B cell growth factor 1; BCDF; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; BSF-1 |
| Accession | P05112-1 |
| Amino Acid Sequence | His25-Ser153 |
| Expression System | HEK293 |
| Molecular Weight | The protein has a predicted MW of 14.96 kDa. Due to glycosylation, the protein migrates to 23-25 kDa based on Bis-Tris PAGE result. |
| Purity | > 95% as determined by Bis-Tris PAGE& HPLC |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor.
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