SKU: 4070153006

FGFR2 Recombinant Rabbit mAb (S-R239)

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Description

FGFR2 Recombinant Rabbit mAb (S-R239)Product Specification Host Rabbit Antigen FGFR2 Synonyms Fibroblast growth factor receptor 2, K sam (KGFR), Keratinocyte growth factor receptor, CD332, BEK, KSAM Location Cell membrane Accession P21802 Clone Number S R239 Antibody Type Recombinant mAb Application ICC, FCM Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300

Product Specification


Host Rabbit
Antigen FGFR2
Synonyms Fibroblast growth factor receptor 2, K-sam (KGFR), Keratinocyte growth factor receptor, CD332, BEK, KSAM
Location Cell membrane
Accession P21802
Clone Number S-R239
Antibody Type Recombinant mAb
Application ICC, FCM
Reactivity Hu
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
ICC 1:500 null
FCM 1:500 null

Background

Fibroblast growth factor receptor 2 (FGFR2) is one of four FGFRs that encode a transmembrane receptor tyrosine kinase. FGFR2 signaling is associated with the proliferation, migration, and angiogenesis of carcinomas. FGFR2-overexpressed cancer might be a therapeutic target. Several FGFR2 inhibitors have been developed for the treatment of cancer patients with enhanced expression of FGFR2 signaling7FGFR2 has two isoforms, i.e., the IIIb type and the IIIc type based on the alternative splicing within the C-terminal half of the third Ig loop (D3) in the extracellular FGF binding domain, which are alternatively spliced by exon 8 and by exon 9, respectively. The spliced isoforms differ in binding ligands: FGFR2IIIb is a high-affinity receptor for FGF1, -3, -7, -10, and -22, whereas FGFR2IIIc binds FGF1, -2, -4, -6, -8, -9 -17 and-18. The FGFR2IIIb isoform is expressed mainly in epithelial cells, and it preferentially binds secreted FGF ligands from adjacent mesenchymal cells. In contrast, the FGFR2IIIc isoform is preferentially expressed in mesenchymal cells and usually binds ligands secreted from the adjacent epithelial cells.

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SKU: 4070153006

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4.6 ★★★★★
Based on 20 reviews
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A
Verified Purchase
Anthony Motley
Omaha, US
★★★★★ 5
Easy to install
Size: 16.5 Inch, Color: White
I bought these for my step daughter for her birthday. I installed them on about 45 minutes. Theyre small and decorative. They're nice to store light weight knick knacks on.
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Reviewed in the United States on May 16, 2026
B
Verified Purchase
Brianna McMichael
Port Orchard, US
★★★★★ 5
Simple, sturdy, and looks great in the room
Size: 16.5 Inch, Color: Rustic Brown
I bought this farmhouse shelf for our bedroom because I needed extra storage that would not make the space feel cramped. After using it for a few weeks, I can say it fits the room really well and does exactly what I hoped it would. The rustic brown color is warm without looking orange or overly dark. It has that farmhouse style but still feels clean and modern. It blends nicely with neutral furniture and does not look cheap or overly distressed. Assembly took me about thirty minutes. The instructions were easy to follow and all the hardware was included. Once everything was tightened, the shelf felt stable and did not wobble. I made sure to assemble it on a flat surface and tighten the screws evenly, which helped keep it level. Right now I am using it for books, a small plant, framed photos, and a storage basket. It handles normal household items without any sagging. I would not overload it with very heavy textbooks on every shelf, but for everyday use in a bedroom or living room, it feels solid. One thing I really like is the size. It gives you good vertical storage without taking up too much floor space. It works especially well in smaller rooms or apartments where you want storage but do not want bulky furniture. If using it in a bathroom, I would just be mindful of humidity over time since the shelves appear to be engineered wood with a laminate finish. For towels and lightweight storage bins, it should work well. Overall, this is a practical and good looking shelf. It is not high end furniture, but it does not feel flimsy either. For the price, I would buy it again.
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Reviewed in the United States on February 25, 2026
O
Verified Purchase
OrangeSlice3
San Leandro, US
★★★★★ 5
Great for the price you pay
Size: 16.5 Inch, Color: Rustic Brown, Size: 16.5 Inch, Color: Rustic Brown
Great shelves for the price you pay. They look good and seem to have good stability so far; we’ll see if anything falls on heads. I put a 6 pack of each up in my son’s rooms and they have all kinds of stuff from katanas to books to knick knacks on them. The shelves aren’t finished so they can leave slivers and might be harder to clean with just a cloth. They came with 6 pieces of wood, not pre-drilled or with any marks for holes, a pack of pretty tough brackets, and all mounting hardware. We used a level, hammer, stud finder, tape measure, the provided wall anchors, long and short screws, pencil, 13/64 drill bit, Phillips head bit, and drill. These helped save space and get rid of some of their clutter.
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Reviewed in the United States on March 10, 2026
K
Verified Purchase
Kailyn
Lexington, US
★★★★★ 3
Not the best.
Size: 16.5 Inch, Color: Rustic Brown, Size: 16.5 Inch, Color: Rustic Brown
The wood style is burned wood without any sealant. I would have given a better rating but some of the shelving was bowed which makes it not look as appealing. Pretty easy to install. Definitely will need your impact. I can’t imagine trying to do that with a hand held screwdriver. With the wood being bent the quality isn’t what I would want it to be. It can hold a decent amount of weight. But certainly not made for books. Even with wall anchors. It gives you the option to hang it as shown in its picture or the other way where the supports are flipped.
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Reviewed in the United States on March 25, 2026
C
Verified Purchase
Chara Reed
Lexington, US
★★★★★ 5
Perfect add to bathroom
Size: 24x6 2Pcs, Color: White
These are perfect. They are just as advertised. They are easy to hang and all needed materials come included (screws and different drywall hanging options).
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Reviewed in the United States on May 18, 2026

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