SKU: 45424583328

APC Mouse Anti-Human CD14 Antibody (S-631-50)

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Description

APC Mouse Anti-Human CD14 Antibody (S-631-50)Product Specification Host Mouse Antigen CD14 Synonyms Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell specific leucine rich glycoprotein Immunogen Recombinant Protein Location Secreted, Cell membrane Accession P08571 Clone Number S 631 50 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0. 05mg ml Conjugation APC Physical Appearance Liquid Storage

Product Specification


Host Mouse
Antigen CD14
Synonyms Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein
Immunogen Recombinant Protein
Location Secreted, Cell membrane
Accession P08571
Clone Number S-631-50
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample human PBMC
Purification Protein G
Concentration 0.05mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD14 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein primarily expressed on monocytes, macrophages, and some granulocytes. It functions as a pattern recognition receptor (PRR) and plays a crucial role in the innate immune response by recognizing bacterial lipopolysaccharides (LPS), pathogen-associated molecular patterns (PAMPs), and damage-associated molecular patterns (DAMPs). CD14 exists in two forms: membrane-bound CD14 (mCD14) and soluble CD14 (sCD14), which can be secreted by activated cells. It acts as a co-receptor for Toll-like receptor 4 (TLR4) and enhances the immune response to LPS by facilitating its delivery to the TLR4-MD2 complex. Additionally, CD14 is involved in TLR4-independent signaling pathways and contributes to tissue homeostasis by promoting the clearance of apoptotic cells.

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SKU: 45424583328

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4.4 ★★★★★
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W
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w+
Port Orchard, US
★★★★★ 3
Good points, but too verbose and in the clouds at times.
Format: Kindle
This book has great points and analysis of trends, and a sensible outlook of what they might lead to. If you already understand the main ideas in this book, it's a good refresher and will solidify your current understanding, but may not really lead to any new "mindblowing" revelations. At times, his head is too in the clouds, and his age shows with predictions that read like bad 1960s sci-fi with things like "computorium" "gray goo" and "nanobots". While his overall points stand strong, some specific technologies he thinks will take off don't seem to have any basis or proof of concept in the real world and might be dead in the water, think "solar freakin roadways" style. He is also very full of himself, repeatedly gloating to the reader of all the "predictions" he made over the years that came true. The biggest weakness of this book is by god does he need an editor, it is way too verbose because the information is not organized well and he repeats himself A LOT. The chapters read like independent blog posts rather than a book due to how repetitive some of his points and information is. Often factoids and paragraphs are bizarrely repeated nearly verbatim pages later. But overall, it's a solid read and those uninitiated to the ideas in this book should absolutely heed their importance.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 10, 2025
C
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chris bickford
West Palm Beach, US
★★★★★ 5
Ray at best
Format: Hardcover
Great ai know how
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Reviewed in the United States on May 20, 2026
L
Verified Purchase
Long Beach Native
Fort Morgan, US
★★★★★ 4
Audiobook has TERRIBLE narrator; book is very techical
Format: Hardcover
So this is a fascinating book -- the author has an incredible depth and breadth of knowledge in a vast array of technical (and medical) subjects. Note this is a much more technical book than your typical science book intended for the educated layperson. That's a big plus for me, but others might be put off by the level of detail. The main fault with the book is the audiobook's narrator, Adam Barr. He has a deep voice that is easy to understand, but he is just about as dull as can be, sounding as if he's reading the ingredients on a can of soup. I ended up buying the hardcover version of the book because the audiobook could not hold my attention -- because of the narrator, not because of the content, which is amazing. I wish more narrators would take a page (ha ha) from talented pros such as Ray Porter and Wil Wheaton. Just because this book is nonfiction doesn't mean it can't be read with heart, as if the reader was speaking to me personally, with enthusiasm, and not just reading words out loud.
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Reviewed in the United States on November 24, 2024
J
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James Walker
Lake Worth, US
★★★★★ 5
The Final Warning
Format: Kindle
No more heads up after this one guys. Ray is not known for missing futurological insights. He’s placed many predictions within this work and it’s my belief that they will occur even sooner than he imagines. That said, the time for comfort with our current way of living is over, and this book functions as the last glance of insight to carry you through with knowledge of what could be. Without it, you are very likely to be entirely blindsighted. The world is changing much faster than the vast majority of people realize. Even those paying close attention to technology. Learn what you can do you can prepare. This book is likely the best way to get ahead of the curve, and adds many new concepts and refinement than the first in the series
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Reviewed in the United States on December 24, 2024
S
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Steve
Boise, US
★★★★★ 5
Superior purchase
Format: Hardcover
Book was in better condition than was advertised. Book was delivered earlier than expected. Book was packaged very very well. Excellent transaction and experience!! Will look forward to purchasing items from this seller in the future! Added bonus-reading the book was a great and thought provoking experience.
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Reviewed in the United States on May 9, 2025

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