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Description
Human GST-π, His tagProduct Specification Species Human Synonyms GST class pi, GSTP1 1, FAEES3, GST3 Accession P09211 Expression System E. coli Molecular Weight Theoretical: 25. 0 kDa Actual: 25. 0kDa Purity 95% by SDS PAGE Endotoxin <1EU mg Tag with C 10*His Physical Appearance Lyophilized Powder Storage Buffer Lyophilized from a 0. 2 m filtered solution of 0. 2M PBS, pH7. 4. Stability & Storage 12 months from date of receipt, 20 to 70 C as supplied. 6 months, 20 to 70
Product Specification
| Species | Human |
| Synonyms | GST class-pi, GSTP1-1, FAEES3, GST3 |
| Accession | P09211 |
| Expression System | E.coli |
| Molecular Weight | Theoretical:25.0 kDa Actual:25.0kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/mg |
| Tag | with C-10*His |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The Glutathione S-transferase π (GST) family of enzymes is a group of typical Phase II detoxification enzymes and is found in many prokaryotes and eukaryotes. Of these enzymes, GSTπ catalyzes the conjunction between GSH and its electrophilic substrates upon exposure to damaging free radicals. Besides metabolite detoxification, GSTπ also exhibits ligand-binding properties that initiate cellular apoptosis when triggered by cellular stress. Further research has also demonstrated that GSTπ is expressed abundantly in tumor cells and associated closely to carcinogenesis, tumor formation, and chemotherapy resistance.
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