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Description
CD8α Rat mAb (S-353-45)Product Specification Host Rat Antigen CD8 Synonyms T cell surface glycoprotein CD8 alpha chain, T cell surface glycoprotein Lyt 2, Lyt 2, Lyt2 Immunogen Recombinant Protein Location Cell membrane Accession P01731 Clone Number S 353 45 Antibody Type Rat mAb Isotype IgG1 Application FCM Reactivity Ms Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03%
Product Specification
| Host | Rat |
| Antigen | CD8α |
| Synonyms | T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, Lyt-2, Lyt2 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | P01731 |
| Clone Number | S-353-45 |
| Antibody Type | Rat mAb |
| Isotype | IgG1 |
| Application | FCM |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:2000 | null |
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen-presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
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