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Description
K9 Advantix II XL Dog Flea, Tick & Mosquito Treatment & PreventionK9 Advantix II Extra Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing
K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Extra Large
Pet Lifestage
- 7 weeks and older
Pet Weight
Over 55 lbs
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.4 ★★★★★
Based on 7 reviews
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Product Reviews
★★★★★ 3
The dog loves 'em
Color: Blue
The dog loves the balls, and they're the right size for my German Shepherd.
Lost a couple of starts because they're not very durable, the "teeth" are easily broken off, so I am frequently finding "lost teeth" across the house; the squeakers also cannot hold up to my dog's aggressive chewing.
I would still buy them again, as like I said, my dog love 'em!
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Reviewed in the United States on February 15, 2026
★★★★★ 5
Dogs love them!
Color: 3 Colors
Dogs love them! Larger than your average tennis balls, satisfying for my dogs to chew on, the squeak isn't too annoying, colorful enough I can find them in the bushes.
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Reviewed in the United States on April 28, 2026
★★★★★ 5
Great product at a great price
Color: 3 Colors
I bought these for my heeler/border collie mix. She destroys every toy almost immediately. They are her favorite toys and plays with them daily. They are still in great shape after 4 months. They have a squeaker, but it is not one of the obnoxious loud ones.
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Reviewed in the United States on April 3, 2026
★★★★★ 5
Fun Dog Fetch Balls
Color: 3 Colors
Ordered these for my dog for Christmas and he loves them. He has a blast running up and down the hallway with them. Easy to play with, cute and fun.
Not very noisy, I actually didn't know they squeaked until I stepped on one. Very quality and sturdy. Good value for the money.
Package arrived timely and as described. Would definitely order again.
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Reviewed in the United States on February 5, 2026
★★★★★ 5
Tough ball. Perfect for large chewing breeds.
Color: 3 Colors
My German Shepherd Dog is a year and half old, and she loves these. They truly are pretty indestructible. It took her a little bit to figure out how to squeak it bc they are tough, but now it’s easy for her. They bounce well too. They are larger than a normal tennis ball but a good size for a large dog. Luna is 85 lbs. I would purchase they again, but I probably won’t need to for awhile.
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Reviewed in the United States on May 17, 2026