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Description
LDHB Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen LDHB Synonyms L lactate dehydrogenase B chain; LDH B; LDH heart subunit (LDH H); Renal carcinoma antigen NY REN 46 Immunogen Synthetic Peptide Location Cytoplasm, Mitochondrion Accession P07195 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HEK 293, HeLa, Jurkat, mouse heart, rat heart Predicted Reactivity Cz, Rb, Du, Ck, Op Purification Immunogen
Product Specification
| Host | Rabbit |
| Antigen | LDHB |
| Synonyms | L-lactate dehydrogenase B chain; LDH-B; LDH heart subunit (LDH-H); Renal carcinoma antigen NY-REN-46 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Mitochondrion |
| Accession | P07195 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HEK-293, HeLa, Jurkat, mouse heart, rat heart |
| Predicted Reactivity | Cz, Rb, Du, Ck, Op |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Hu, Ms, Rt |
| IHC-P | 1:250 | Hu, Ms, Rt |
Background
LDHB protein, encoded by the LDHB gene, is a subunit of the lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with the concomitant interconversion of NADH and NAD+ in a post-glycolysis process. This enzyme exists in five different forms, each composed of four subunits, with LDHB subunits combining with LDHA subunits to form various isozymes. The LDHB gene is located on chromosome 12p12.1 and encodes a protein of 334 amino acids. Mutations in the LDHB gene can lead to lactate dehydrogenase B deficiency, but this condition typically does not cause any physical signs or symptoms.
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