SKU: 52967835008

Alexa Fluor® 647 Mouse Anti-Human CD18 Antibody (S-R487)

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Description

Alexa Fluor® 647 Mouse Anti-Human CD18 Antibody (S-R487)Product Specification Host Mouse Antigen CD18 Synonyms Integrin beta 2; Cell surface adhesion glycoproteins LFA 1 CR3 p150,95 subunit beta; Complement receptor C3 subunit beta; MFI7; ITGB2 Location Cell membrane Accession P05107 Clone Number S R487 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage

Product Specification


Host Mouse
Antigen CD18
Synonyms Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; MFI7; ITGB2
Location Cell membrane
Accession P05107
Clone Number S-R487
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD18, also known as integrin β2, is a 95 kDa glycoprotein that is a crucial component of several β2 integrins. These integrins are heterodimeric type I transmembrane proteins composed of a variable alpha chain (CD11a-d) and the common beta chain CD18. The CD18 protein is encoded by the ITGB2 gene in humans. It plays a significant role in cellular adhesion and immune responses. When CD18 binds with different alpha chains, it forms various heterodimers such as lymphocyte function-associated antigen-1 (LFA-1) with CD11a, and Macrophage-1 antigen receptor (Mac-1) with CD11b. These heterodimers are involved in processes like leukocyte adhesion to endothelial cells, phagocytosis, and immune cell activation. Deficiencies in CD18 expression can lead to adhesion defects in white blood cells, impairing the immune system's ability to fight infections.

Shipping Notes
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Exchange/Return Notes
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SKU: 52967835008

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4.7 ★★★★★
Based on 27 reviews
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Product Reviews
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Verified Purchase
David Robles
Alexandria, US
★★★★★ 5
Love them!!!
Size: 8, Color: Black/White/Black
Great!!!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 6, 2026
E
Verified Purchase
Eduardo Renta
Cuba, US
★★★★★ 5
⭐⭐⭐⭐⭐ Clean Look, Comfortable Ride
Size: 11.5 Wide, Color: Woodbury Handstain
The Cole Haan Men’s GrandPro Tennis sneakers are a perfect mix of laid-back and polished — the kind of shoe you can wear everywhere without thinking too hard about it. Right off the bat, the design is subtle but refined. They’re minimalist enough to pair with jeans and a hoodie, but they also work with chinos and a button-down for a more put-together look. The “tennis” aesthetic keeps it classic without feeling like you’re wearing athletic shoes. Comfort is where these really shine. They’re lightweight and cushioned in all the right places, so long walks, errands, or standing around at events don’t end with sore feet. There’s no stiff break-in period — they feel good from the first wear. The sole has just the right balance of support and flexibility, which makes them easy to wear all day. The materials feel good too — soft, sturdy, and not flimsy. They hold up well after repeated wear and still look fresh even after a few outings. They don’t crease or scuff up excessively, which is always nice. If I had to point out a downside, it’s that they’re not performance sneakers for athletics — but that’s not what they’re meant to be. They’re lifestyle shoes that look great and feel great for everyday wear. Overall, a solid go-to sneaker that elevates casual outfits and keeps comfort front and center. Easy recommend if you want versatile kicks that stay stylish without being loud. I was able to pick up this particular pair here on Amazon for 50 bucks, 56 total with everything and honestly I’m still scratching my head in that deal. I mean my New Balance were 70 bucks or something like that. These are brown leather, sophisticated and comfortable, just amazing shoes. I get compliments all the time.
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Reviewed in the United States on February 16, 2026
D
Verified Purchase
Deborah Barnum
Port Orchard, US
★★★★★ 5
Quality and Comfort
Size: 12, Color: White
My husband is a Cole Haan shoe person and what we love mostly is the comfort and quality and style.
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Reviewed in the United States on May 13, 2026
S
Verified Purchase
superbrain
Massapequa, US
★★★★★ 5
Size seems spot on shoe is beautiful
Size: 12, Color: White
These are beautiful shoes. A great cross between the ubiquitous flat as a board shoes like vans and tennis shoes. More comfortable than the super flat shoes and more formal than sneakers. Very soft leather. Not much arch support and I don't know if an insert would fit well. I am between an 11.5 and 12 in most brands (actual foot length from heel to tip of big toe is 11 and 1/8 inches). These fit perfectly in a 12 with room for comfort. An 11.5 probably would fit but snugly. I do not agree that they should be sized down at least based on my experience. If you can get these for under eighty dollars like I did they are well worth it. I'll be wearing them all summer.
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Reviewed in the United States on May 15, 2021
I
Verified Purchase
It's cool.
Natrona Heights, US
★★★★★ 4
Weightless, well made. But there are problems with size
Size: 8.5, Color: White
I bought it for a teenager, for size 81/2. This, according to the dimensions on the page, is 25.9 centimeters. They came, the size was indicated correctly, but they are large for the child. Very large. They fit me, size 10. The child is disappointed. Well made, look neat on the foot. Almost weightless But I can't give the maximum rating. I wish the seller to deal with the size grid.
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Reviewed in the United States on April 15, 2026

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