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Description
Biotin Mouse Anti-Rat CD4 Antibody (S-R631)Product Specification Host Mouse Antigen CD4 Synonyms T cell surface glycoprotein CD4; T cell surface antigen T4 Leu 3; W3 25 antigen; Cd4 Location Cell membrane Accession P05540 Clone Number S R631 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Rt Positive Sample SD Rat splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Biotin Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Mouse |
| Antigen | CD4 |
| Synonyms | T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; W3/25 antigen; Cd4 |
| Location | Cell membrane |
| Accession | P05540 |
| Clone Number | S-R631 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Rt |
| Positive Sample | SD Rat splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Rt |
Background
CD4 is a glycoprotein expressed on the surface of certain immune cells, most notably helper T cells. It is a member of the immunoglobulin superfamily and has four immunoglobulin-like domains (D1 to D4). CD4 acts as a co-receptor with the T-cell receptor (TCR) to recognize antigens displayed by MHC class II molecules on antigen-presenting cells. The D1 domain of CD4 binds to the β2 region of MHC class II, bringing the TCR complex and CD4 into close proximity. This allows the tyrosine kinase Lck, bound to the cytoplasmic tail of CD4, to phosphorylate tyrosine residues on the cytoplasmic domains of CD3, amplifying the signal generated by the TCR. CD4 is also the primary receptor for the human immunodeficiency virus (HIV), and its interaction with the HIV gp120 protein is a key step in viral entry.
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4.5 ★★★★★
Based on 17 reviews
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Product Reviews
★★★★★ 3
Thin, summer weight throw, quality could be better
Color: Southern Blues, Size: Throw (50 in x 60 in), Color: Southern Blues, Size: Throw (50 in x 60 in)
This is a very light weight blanket and the "fleece" is no where to be seen. The blanket looks like cotton but has a very synthetic feel to it. Three layers implies some weight but it is thin.
The construction is sloppy, see images, where the stitching looks slap dash to the point where it cannot be reversed.
I liked the color, the blue is a little on the aqua side but it is a very nice calming hue. The stitching is quilt like and nicely done.
I noticed other reviews felt like it was a medium weight but the only time I would use this would be to use as a cover if the AC went out. To me, the blanket is decorative and not particularly useful.
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Reviewed in the United States on May 15, 2026
★★★★★ 4
Average quality lightweight throw, not sold on the color
Color: Southern Blues, Size: Throw (50 in x 60 in), Color: Southern Blues, Size: Throw (50 in x 60 in)
This blanket is fairly soft and lightweight, and better suited for the summer months. I don't think the texture and "Southern Blues" color looks as nice in person as in the photos; less cozy and more like a spare blanket you might find in a hotel closet.
Interestingly the care tag says that the outer faces are cotton, but the blanket feels polyester and the content tag indicates the same. The stitching and durability feel ok, and it will probably hold up for the occasional machine washing and low heat drying.
Overall it's a fine warm season throw but not particularly notable. I would probably recommend one of the darker colors.
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Reviewed in the United States on May 23, 2026
★★★★★ 5
So easy to wash!
Color: Southern Blues, Size: Full/Queen (90 in x 90 in), Color: Southern Blues, Size: Full/Queen (90 in x 90 in)
Two things I love about this coverlet:
1. It's so much easier to wash than a duvet! Or even a duvet cover or a regular blanket, for that matter. The queen-size coverlet fit easily in my washer, and I could have put in another if I had had one. It stayed loose and balanced in the machine - the washer didn't have to readjust its balance during the spin cycles. In the dryer, it didn't wad up into a ball that had to be shaken out every few minutes. It came out feeling softer and looking good, with no wrinkles.
2. It's thinner than a duvet and suitable for warm weather, yet those three stitched layers give it substance and weight that I find more comfortable than sleeping under a pile of fluff or a bed sheet.
The soft pastel green color with cream lining (not really reversible due to the hem) is fresh and reminiscent of the 1950s coverlets that my grandmother made. Crocheting was one of her passions, and she'd create huge lacy doilies that lay across the foot of the coverlet. Very pretty look.
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Reviewed in the United States on May 1, 2026
★★★★★ 5
Great summer blanket.
Color: Black, Size: Full/Queen (90 in x 90 in)
I purchased this Berkshire 3-layer fleece blanket, and it has quickly become my go-to for my queen size bed. It fits perfectly with plenty of overhang, making it look great as a top layer or a middle layer.What I love most is the breathability. While the material is technically fleece, the 3-layer design provides a nice "cotton-like" feel that doesn't feel heavy or stifling. I tend to sleep hot, and this blanket does a fantastic job of keeping me cool and comfortable through the night while still providing just enough cozy warmth.At this price point, the value is good. It feels much higher quality than other thermal blankets I’ve tried, and it holds up well in the wash without pilling or losing its softness. If you're looking for a versatile, lightweight blanket that works year-round, this is a solid choice. Highly recommended!
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Reviewed in the United States on May 9, 2026
★★★★★ 5
Soft, Warm, lightweight, Cozy
Color: Cream, Size: Full/Queen
When I first received this blanket I washed it by itself in cold water with detergent. I did not use a fabric softener or a fabric sheet. I air dried it completely and then put it in my dryer on air fluff for 10 minutes. No shedding and it came out just like I received it. I was concerned about shedding with some of the reviews but I had no issues with that whatsoever. It's warm yet lightweight. I didn't want anything that would make me overly hot because I'm always hot anyway. It takes that cool edge off when you still want your overhead fan on. My daughter said she likes it better than the one she has. I can't remember the brand. I feel it has a good quality. Just make note to wash it as instructed and it'll hold up well and look just as nice as the way you bought it. I'm not sure how the other reviewers that didn't leave 5 stars washed there's, but it couldn't have been the correct way.
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Reviewed in the United States on September 20, 2025
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