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Description
APC-Cy7 Mouse Anti-Human CD8 Antibody (S-R533)Product Specification Host Mouse Antigen CD8 Synonyms T cell surface glycoprotein CD8 alpha chain; T lymphocyte differentiation antigen T8 Leu 2; MAL; CD8A Location Cell membrane Accession P01732 Clone Number S R533 Antibody Type Mouse mAb Isotype IgG1 Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0. 05mg ml Conjugation APC Cy7 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300
Product Specification
| Host | Mouse |
| Antigen | CD8α |
| Synonyms | T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; MAL; CD8A |
| Location | Cell membrane |
| Accession | P01732 |
| Clone Number | S-R533 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1 |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human PBMC |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | APC-Cy7 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD8α is a crucial immune glycoprotein that plays a vital role in the immune response by serving as a co-receptor for the T-cell receptor (TCR) on cytotoxic T cells. It forms either a homodimer (α/α) or a heterodimer with CD8β (α/β) to interact with MHC class I molecules on antigen-presenting cells (APCs), facilitating the recognition of intracellular pathogens such as viruses. CD8α also recruits the LCK kinase, which initiates downstream signaling pathways essential for T-cell activation and proliferation. This molecule is critical for the function of cytotoxic T lymphocytes (CTLs) and is involved in various immune-related diseases, including immunodeficiencies and autoimmune conditions.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.0 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 5
The only chew toy that has actualy held up...for well over 2 years!
Size: Medium, Style: 4 Pack, Size: Medium, Style: 4 Pack
These things are amazing! They last forever even with dogs that can destroy nearly everything else in mins! I ordered these as a doggie Xmas gift over TWO YEARS AGO, and they are still pretty much fully intact! They chew on them all the time, too!(see pics; that's over two years of steady use!) I only got the one 4 pack, and have 4 dogs, too!
Since making them so well does kind of reduce my ability to buy many more from them, I feel I should at least let people know they really are crazy durable and dogs love them! I will prob buy another 4 pack soon, just so they are easier to find(end up under couches,etc). Def a good buy!!!!
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Reviewed in the United States on May 10, 2026
★★★★★ 5
Built for heavy chewers and actually holds up
Size: Medium, Style: Fishbone/Wishbone
This chew toy is a total win for heavy chewers and has held up really well compared to so many others we’ve tried. It keeps dogs busy for long stretches and they stay genuinely interested in it instead of destroying it in minutes. The shape makes it easy for them to grip and chew comfortably, which adds to how much they use it. The durability is the real standout here, making it one of those rare toys that actually earns a repurchase. The material feels sturdy, it’s easy to clean, and there’s no noticeable odor, which is always a plus.
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Reviewed in the United States on May 2, 2026
★★★★★ 5
Definitely recommend
Size: Large, Style: 4 Pack
My dogs absolutely love these! I bought them at a great price! They have lasted my dogs over a year! I have a full pitbull, pit/lab, pit/boxer, and a pit/mastiff. So needless to say they pass the power jaw test. They look just like the pictures and they are pretty light weight!
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Benebone is fantastic for heavy chewers and busy, adolescent pups!
Size: Medium, Style: 4 Pack
This little multi-pack is cost-effective in a few ways, super durable and effective, and I'll definitely be purchasing the multi-pack again. We discovered these about a year ago and have been buying them ever since. I'm just now getting around to reviewing them because they're that good, plus I love that the company is family-owned.
Four "bones" lasts a little over a month for a power chewer, which is a bargain! You get 4 medium size "bones" for the retail price of 2. These smell delicious to dogs but humans can detect the odor, which is so nice. They are incredibly durable, but somehow also not too hard for a power chewer, and they keep pup from chewing on books and other items that we don't wanted chewed to bits. Heavy chewers (and their people!) love these and the variety of shapes means we can swap them out in rotation and keep pup's interest going for a few weeks.
Wait until your pup has all of their adult teeth, as they are a little too hard for teething. And for super power chewers, watch out for the fish shaped chew, as this one seems to allow larger pieces to be chewed off the fish head "corners" more easily due to the relative thinness of the shape at that point when compared to the other 3 shapes.
Keep an eye on how much your power chewer is taking off of these "bones" (little tiny pieces do get chewed off) and toss them (or recycle with Benebone!) when your dog is able to chew off more than a crumb size piece.
Hooray for Benebone! Hooray for family-owned businesses! We'll be back for more!
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Reviewed in the United States on April 7, 2025
★★★★★ 4
Seems Very Durable So Far
Size: Small, Style: 4 Pack
My dogs are really enjoying these chew toys! These keep them busy for hours!! So far they seem very durable and my little dogs can really chew and destroy so I’m happy about these so far! They rarely each chew a toy at the same time, but choose to take turns instead. But now they each have a chew toy and they are happy campers!!
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Reviewed in the United States on January 1, 2026
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