SKU: 58898965443

Rat Anti-Mouse CD25 (IL-2Rα) Antibody (S-3558)

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Description

Rat Anti-Mouse CD25 (IL-2Rα) Antibody (S-3558)Product Specification Host Rat Antigen CD25 Synonyms Interleukin 2 receptor subunit alpha; IL 2 receptor subunit alpha; IL 2 RA; IL 2R subunit alpha; IL2 RA; p55; Il2r; Il2ra Location Membrane Accession P01590 Clone Number S 3558 Antibody Type Rat mAb Isotype IgG1, Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS

Product Specification


Host Rat
Antigen CD25
Synonyms Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; p55; Il2r; Il2ra
Location Membrane
Accession P01590
Clone Number S-3558
Antibody Type Rat mAb
Isotype IgG1,λ
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Ms

Background

CD25, also known as the interleukin-2 receptor alpha chain (IL2RA), is a type I transmembrane glycoprotein that plays a crucial role in the immune system. It is primarily expressed on the surface of activated T cells and regulatory T cells (Tregs). CD25 is a key component of the high-affinity IL-2 receptor complex, which also includes the IL-2 receptor beta and gamma chains. By itself, CD25 can bind IL-2 with low affinity, but when combined with the beta and gamma chains, it forms a high-affinity receptor that initiates intracellular signaling pathways such as MAPK and JAK/STAT. This receptor complex is essential for the proliferation and activation of T cells, as well as the regulation of immune tolerance by controlling the activity of Tregs. Mutations in the IL2RA gene can lead to deficiencies in IL-2 receptor function, highlighting its importance in maintaining immune homeostasis.

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SKU: 58898965443

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Reviewed in the United States on March 30, 2026
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Battle Creek, US
★★★★★ 5
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Size: 10 Inch, Unit Count: 372.0
Paper plates are something you really need to shop around and these from Amazon are well made and priced to sell. They hold up well when we are looking to have a quick bite for lunch or a midday snack.
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Reviewed in the United States on May 9, 2026
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Massapequa, US
★★★★★ 5
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Size: 32 Ounce (Pack of 1)
I recently picked up the Queen Helene Cocoa Butter Hand & Body Lotion, and I have to say, it’s quickly become a staple in my skincare routine. The first thing I noticed was the rich, creamy texture. It glides on smoothly and doesn’t leave that greasy feeling that some lotions do, which is a huge plus for me. The cocoa butter scent is delightful but not overwhelming. It reminds me of a warm, cozy day, and it lingers just enough to be pleasant without being too much. I usually apply it after my showers, and my skin feels so hydrated and soft for hours afterward. I also appreciate that it comes in a big 32 oz size. I feel like I’m getting good value for my money, and I don’t have to worry about running out anytime soon. Plus, it’s versatile—perfect for both my hands and body. Overall, I’ve enjoyed using this lotion, and it’s definitely helped to keep my skin feeling moisturized, especially as the weather gets colder. If you’re looking for a budget-friendly option that really delivers on hydration and has a lovely scent, I’d recommend giving this one a try!
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Reviewed in the United States on October 9, 2025
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Mindee L.
Dallas, US
★★★★★ 5
Queen Helene Cocoa Butter Hand and Body Lotion
Size: 32 Ounce (Pack of 1), Size: 32 Ounce (Pack of 1)
As someone who typically shies away from using lotion due to its heavy and greasy feel, I was initially hesitant to try the Queen Helene Cocoa Butter Hand and Body Lotion. However, after ordering a large bottle for both my husband and me, I can confidently say that I am pleasantly surprised by how much I love it. One of the first things that struck me about this lotion is its delightful scent. With every application, I feel like I've been transported to a serene beach setting, enveloped in the comforting aroma of cocoa butter. It adds a touch of luxury to my skincare routine and leaves me feeling refreshed and rejuvenated. What truly sets this lotion apart for me is its lightweight texture. Unlike other lotions I've tried in the past, this one absorbs quickly into the skin without leaving behind any greasy residue. I appreciate how effortlessly it spreads and how it doesn't weigh down my skin, allowing me to go about my day comfortably. Additionally, I've noticed that the Queen Helene Cocoa Butter Hand and Body Lotion provides ample hydration without feeling heavy or cloying. It leaves my skin feeling soft, smooth, and moisturized, without the need for constant reapplication throughout the day. I would highly recommend this lotion, especially for those with mature skin. Its lightweight, non-greasy formula makes it a joy to use, and the beach-like scent adds a delightful touch to the skincare experience. Overall, I'm thoroughly impressed with the Queen Helene Cocoa Butter Hand and Body Lotion and plan to continue incorporating it into my daily routine.
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Reviewed in the United States on February 11, 2024
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Martha
Pawtucket, US
★★★★★ 5
Leaves skin soft and smooth.
Size: 3 Pack (16 Ounce)
Quality lotion pleasant fragrance.
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