SKU: 60874307336

IL13RA2/IL13R Fc Chimera Protein, Human

$252.00 $280.00
Save 10%
No.2 Bestseller on 2pierres.com >

Pay in installments of $70.00 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 11 - Aug 16

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

IL13RA2/IL13R Fc Chimera Protein, HumanProduct Specification Species Human Synonyms IL 13 receptor subunit alpha 2, IL 13R subunit alpha 2, IL 13R alpha 2, IL 13RA2, nterleukin 13 binding protein, Interleukin 13 receptor subunit alpha 2, IL13RA2 Accession Q14627 Amino Acid Sequence Asp27 Arg343, with C terminal hIgG1 Fc Expression System HEK293 Molecular Weight 73 89kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag Human Fc Tag Physical Appearance

Product Specification


Species Human
Synonyms IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, IL-13R-alpha-2, IL-13RA2, nterleukin-13-binding protein, Interleukin-13 receptor subunit alpha-2, IL13RA2
Accession Q14627
Amino Acid Sequence Asp27-Arg343, with C-terminal hIgG1 Fc
Expression System HEK293
Molecular Weight

73-89kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag Human Fc Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.
Reference

Kawakami K, Kawakami M, Puri R. Specifically targeted killing of interleukin-13 (IL-13) receptor-expressing breast cancer by IL-13 fusion cytotoxin in animal model of human disease. Mol Cancer Ther. 2004; 3:137–147. Valverde A, Povedano E, Montiel V, Yanez-Sedeno P, Garranzo-Asensio M, Barderas R, Campuzano S, Pingarron J. Electrochemical immunosensor for IL-13 Receptor alpha2 determination and discrimination of metastatic colon cancer cells. Biosens Bioelectron. 2018; 117:766–772. Okamoto H, Yoshimatsu Y, Tomizawa T, Kunita A, Takayama R, Morikawa T, Komura D, Takahashi K, Oshima T, Sato M, Komai M, Podyma-Inoue K, Uchida H, Hamada H, Fujiu K, Ishikawa S, Fukayama M, Fukuhara T, Watabe T. Interleukin-13 receptor alpha2 is a novel marker and potential therapeutic target for human melanoma. Sci Rep. 2019; 9:1281. Husain S, Puri R. Interleukin-13 receptor-directed cytotoxin for malignant glioma therapy: from bench to bedside. J Neurooncol. 2003; 65:37–48. Tu M, Wange W, Cai L, Zhu P, Gao Z, Zheng W. IL-13 receptor alpha2 stimulates human glioma cell growth and metastasis through the Src/PI3K/Akt/mTOR signaling pathway. Tumour Biol. 2016; 37:14701–14709. D.D. Donaldson, M.J. The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1. J. Immunol., 161 (1998), pp. 2317-2324

Background

Interleukin-13 receptor subunit alpha-2 (IL13RA2) is a high-affinity membrane receptor of IL-13 and is abundantly expressed in a variety of tumors, such as pancreatic cancer, ovarian cancer, breast cancer, colon cancer and melanoma. IL13RA2 is a glycosylated protein containing four potential glycosylation sites. IL13RA2 was initially considered a second, decoy receptor for interleukin 13 (IL-13). IL13RA2 is upregulated during helminthic and parasitic infections (i.e. schistosomiasis) as IgE is a key molecule in the fight against parasites and IL-13 is required for the IgE switching. A IL13RA2, an immunotherapeutic target, is considered a promising direction for the treatment of glioma.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 60874307336

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.5 ★★★★★
Based on 6 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
D
Verified Purchase
Divulge
Massapequa, US
★★★★★ 5
Love this product
Size: 6 Fl Oz (Pack of 2)
Love this product. The only product I would use on my face
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 19, 2026
E
Verified Purchase
Emma Wilson
Los Angeles, US
★★★★★ 5
Not greasy at all
Size: 6 Fl Oz (Pack of 2)
This is my first mineral sunscreen. I love that it is not greasy at all. It's easy to apply, and hasn't caused any irritation to my baby's skin.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 24, 2025
F
Verified Purchase
FW
New York, US
★★★★★ 5
Fantastic start up
Truskin products are fantastic in my opinion. Not expensive AND effective.. what more can you ask. This 3 pack with Hyaluronic acid, Retinol, and Vitamin C is perfect. I go through the HA faster than the rest so I end up buying the bigger bottle of it. The Vitamin C serum feels incredible on my skin. It feels more moisturizing than the HA. I love using it- just please don’t forget the SPF. This combo pack is perfect for anyone looking to care for their skin. I don’t notice any off putting odors. They all dry down quickly. My skin has not reacted poorly to any of the products. I do stick to my routine of actives(retinol, vit c, tea tree- rotated)to 3x a week and the other days are gentle cleansing, moisturizer and SPF. Since I have switched my skin care routine to TruSkin, I have noticed better looking skin. I’m moisturized with soft youthful looking skin. Recommend and will be buying more.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 5, 2026
A
Verified Purchase
Angelsmom
Cuba, US
★★★★★ 5
I didn’t expect this to actually work.
I didn’t take a before photo. Because I legit didn’t expect this to do anything to my skin. I’ve used similar serums before with no results. But here I am, spreading the word because I’m a believer. To describe my skin: aging (mid 40’s), a few wrinkles here and there, nothing insane, very fair, super dry, with an oddly greasy forehead. Minor sun damage, uneven texture and big fat pores that I loathe. Occasional zit here and there. I also have rosacea. It’s the kind of rosacea that turns me bright red when I’m overheated or angry, or if I rub my face too much. It’s doesn’t change the texture or anything, just turns me bright red. My dermatologist prescribed me a cream for it, but warned me that it is the kind of rosacea that is not always easy to treat because it comes from deep under the skin and is situational. The cream was short lived because it dried me out severely. I recently had a trusted friend who is also an oculoplastics surgeon suggest a good vitamin c serum and retinol. He didn’t suggest a brand, just use of the product. So I went hunting on Amazon. This product had great reviews. I figured I’d invest in the three pack since I also knew Hyaluronic acid was a must. My first impressions: Shortly after I ordered it, hadn’t yet received, I got an email from the company offering assistance if needed and gratitude for purchasing product. Good to know I had that standing by if needed. Who doesn’t appreciate a business committed to having happy customers? My first impression for my first uses of the products was positive. Obviously it was too early to see any noticeable changes, but I did like that the serums don’t have smells, they dried very quickly and they’re super easy to rub in. A little goes a long way too. I’m going to reiterate that they don’t smell. Many products say ‘unscented’ but you can still smell something, bad or good. The only one I can mildly smell is the hyaluronic acid and it smells pleasant and clean, but even then, I can barely smell it when I first start rubbing it in. Any smell is gone almost instantly. I can’t describe the smell because by the time my brain realizes I’m smelling something, the smell is already gone. So that’s nice! My impression now, after using it a while: I love it! My redness is greatly reduced. In addition to my rosacea, my very fair skin can be somewhat translucent in places and kind of reveals the semblance of some blood vessels under my skin. This has minimized them tremendously. My “elevens” are lessened as well. This was a big surprise…that wrinkle, along with some wrinkling around my eyes has noticeably lessened. And I want to reiterate that this is all easily noticeable to me without a before photo. It is hard to notice subtle, gradual changes when we don’t have a photo for before and after comparisons - but I’ve noticed. I introduced another item from another brand, and I think that it’s has helped greatly with my pores but I believe these serums have helped too- my pores are barely visible. I am also very impressed by the texture of my skin. I have ALWAYS struggled with uneven texture. I’ve done all the texture improving techniques, tried the products claiming to improve texture, everything I knew to do, with no real difference. But this- this changed the feel of my facial skin entirely. I bumped my own cheek a couple days ago and actually had to rub my face again to ensure it was MY skin I was feeling. It was like a tactile double take. Why? Because my skin was silky smooth. My makeup wears so much better on my skin. My skin looks noticeably younger and brighter and I haven’t had any new zits either since I started. I cannot express enough how happy I am with these changes and these serums. I truly expected these to be items I ended up not using and simply giving them away. But these are staples now. They are worth every penny and a bargain for the skin changes. I look forward to seeing more improvements in my skin over time and I highly recommend this product to any skeptic like I was.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 12, 2025
A
Verified Purchase
Amazon Customer
San Leandro, US
★★★★★ 5
Great stuff definitely recommend at least trying
I've been using the TruSkin Vitamin C serum for over a year, and it's done a solid job brightening my complexion and fading dark spots. Finally gave the full Face Serum Trio a shot with the hyaluronic acid and retinol, and after about a month, it's working great, just like the Vitamin C. The hyaluronic acid hydrates my skin well without any grease, and the retinol's knocked down some fine lines, making things smoother and fresher. Layering them has improved the texture and glow noticeably. No irritation on my sensitive skin. Solid value—I picked this up at $26 when it was Prime Day, but even at that $40 price range, it's still worth it in my opinion since it can last a while. Definitely recommend
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 1, 2025

recommand products

Hands
51.00
Desire & Bob Dylan & Empire Burlesque
45.56
Beneath a Meth Moon
64.00
Otis and the Tornado
128.00
Giving Thanks
122.00