SKU: 61371089576

PTK7/CCK4 His Tag Protein, Mouse

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Description

PTK7/CCK4 His Tag Protein, MouseProduct Specification Species Mouse Synonyms PTK7, CCK4, Colon carcinoma kinase 4, Inactive tyrosine protein kinase 7, Tyrosine protein kinase like 7 Accession Q8BKG3 Amino Acid Sequence Ala23 Thr696, with C terminal 10*His

Product Specification


Species Mouse
Synonyms PTK7, CCK4, Colon carcinoma kinase 4, Inactive tyrosine-protein kinase 7, Tyrosine-protein kinase-like 7
Accession Q8BKG3
Amino Acid Sequence Ala23-Thr696, with C-terminal 10*His AIVFIKEPSSQDALQGRRALLRCEVEAPDPVHVYWLLNGVPVQDTERRFAQGSSLSFAAVDRLQDSGAFQCVARDNVTGEEVRSTNASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDDQSTHTVSSRERNLTLRPASPEHSGLYSCCAHNAFGQACSSQNFTLSVADESFARVVLAPQDVVVARNEEAMFHCQFSAQPPPSLQWVFEDETPITNRSRPPHLRRAVVFANGSLLLTQVRPRNAGVYRCIGQGQRGPPIVLEATLHLAEIEDMLPFEPRVFIAGDEERVTCPAPQGLPTPSVWWEHAGVPLPAHGRVHQKGLELVFVTIAESDTGVYTCHASNLAGQRRQDVNITVATVPTWLRKPQDSQLEEGKPGYLHCLTQATPKPTVIWYRNQMLISEDSRFEVSKNGTLRINSVEVYDGTLYRCVSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTVKWVRADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNEPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLRCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGSYTCIAGNSCNIRHTEAPLLVVDKPVMEDSEGPGSPPPYKMIQTGGGSGGGSHHHHHHHHHH
Expression System HEK293
Molecular Weight 95-110kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Lichtig H. et al. (2019) Ptk7 proteolytic fragment proteins function during early xenopus development. Dev Biol. 453(1): 48-55.

2、Damelin M. et al. (2017) A ptk7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions. Sci Transl Med 9 (372): eaag2611.

Background

Protein tyrosine kinase 7 (PTK7), also known as colon carcinoma kinase 4 (CCK4), is a member of the receptor tyrosine kinase superfamily. PTK7 is a type I transmembrane receptor with a large extracellular domain (ECD) containing 7 Ig-like C2 type loops, a transmembrane domain, and a cytoplasmic tyrosine kinase homology domain. PTK7 has been shown to be an important regulator of the Wnt signaling pathways, both canonical and non-canonical, and is linked to the regulation of the planar cell polarity pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
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SKU: 61371089576

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Jennuh G.
Birmingham, US
★★★★★ 5
Cute outfit for everyday.
Size: 2T, Color: Pink/Unicorn
Exactly as pictured. Good quality, not too thin but also not too thick. True to size and looks like it will keep my baby warm when she’s inside. Good price on sale! Was a steal!
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Reviewed in the United States on December 13, 2025
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K.B
Natrona Heights, US
★★★★★ 5
High Quality
Size: X-Small, Color: Pink/Unicorn
High print quality, and vivid colors. Got exactly what I expected.
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Reviewed in the United States on December 25, 2025
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Tsia
Lake Worth, US
★★★★★ 4
Just as pictured
Size: X-Large, Color: Mauve/Apples
It is sized big so I suggest that you order a size down.other than that it is just as pictured.
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Reviewed in the United States on November 13, 2025
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Cynthia
Chelsea, US
★★★★★ 5
Good
Size: Medium, Color: Pink/Unicorn
Fits as expected.
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Reviewed in the United States on March 26, 2026
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Tam I M
Whiting, US
★★★★★ 5
Great quality
Very comfortable and good quality we have washed it multiple times and still looks great
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Reviewed in the United States on November 24, 2025

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