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Description
S-RMab® Desmin Recombinant Rabbit mAb, PBS Only (SDT-109-114)Product Specification Host Rabbit Antigen Desmin Synonyms DES Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Cell membrane, Intermediate Filament Accession P17661 Clone Number SDT 109 114 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IF, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date
Product Specification
| Host | Rabbit |
| Antigen | Desmin |
| Synonyms | DES |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Cell membrane, Intermediate Filament |
| Accession | P17661 |
| Clone Number | SDT-109-114 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IF, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500 | |
| ICC | 1:500 | |
| IF | 1:500 | |
| ICFCM | 1:500 |
Background
Desmin is a 53 kDa muscle -specific molecule, which belongs to the middle silk super family of cell skeleton protein. Cyclical protein digosum formation forms a stable wire -shaped network, which can stabilize the horizontal arrangement of the muscle fiber. Most mutations affect filament assembly. Desmin knockout mice will form myocardial disease, skeletal muscle defects and smooth muscle defects. It is a good screening symbol of tumor with muscle-derived differentiation, including transverse muscle sarcoma, horizontal fibroids, smooth muscle sarcoma, smooth fibroids, smooth muscles, and horizontal muscle cells in other tumors.
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