Pay in installments of $27.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 9 - Sep 14
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
FITC Armenian hamster Anti-Mouse/Human Helios Antibody (S-R640)Product Specification Host Armenian hamster Antigen Helios Synonyms Zinc finger protein Helios; Ikaros family zinc finger protein 2; IKZF2; ZNFN1A2 Location Nucleus Accession Q9UKS7 P81183 Clone Number S R640 Antibody Type Recombinant mAb Isotype IgG Application ICFCM Reactivity Hu, Ms Positive Sample Human PBMC Purification Protein G Concentration 0. 05mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0. 3%
Product Specification
| Host | Armenian hamster |
| Antigen | Helios |
| Synonyms | Zinc finger protein Helios; Ikaros family zinc finger protein 2; IKZF2; ZNFN1A2 |
| Location | Nucleus |
| Accession | Q9UKS7、 P81183 |
| Clone Number | S-R640 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | ICFCM |
| Reactivity | Hu, Ms |
| Positive Sample | Human PBMC |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | FITC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ICFCM | 5μl per million cells in 100μl volume | Hu, Ms |
Background
Helios protein (encoded by the IKZF2 gene) is a member of the Ikaros family of transcription factors and contains multiple zinc finger domains that facilitate DNA binding and the formation of homodimers or heterodimers. It is predominantly expressed in T cells, regulatory T cells (Tregs), certain B cell subsets, and hematopoietic and epithelial tissues. Helios plays a crucial role in T cell activation, proliferation, and the stability and function of Tregs. Additionally, Helios has been identified as a potential biomarker in autoimmune diseases and may influence tumor development by regulating gene expression and modulating cell differentiation and proliferation.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy