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Description
KIM-1 Recombinant Rabbit mAb (S-932-2)Product Specification Host Rabbit Synonyms Hepatitis A virus cellular receptor 1, HAVcr 1, Kidney injury molecule 1, T cell immunoglobulin and mucin domain containing protein 1 (TIMD 1), T cell immunoglobulin mucin receptor 1, T cell membrane protein 1, CD365, HAVCR1, KIM1, TIM1, TIMD1 Immunogen Recombinant Protein Location Cell membrane Accession Q96D42 Clone Number S 932 2 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, FCM, IP
Product Specification
| Host | Rabbit |
| Synonyms | Hepatitis A virus cellular receptor 1, HAVcr-1, Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1), T-cell immunoglobulin mucin receptor 1, T-cell membrane protein 1, CD365, HAVCR1, KIM1, TIM1, TIMD1 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | Q96D42 |
| Clone Number | S-932-2 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, FCM, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC-P | 1:500 | null |
| ICC | 1:500 | null |
| FCM | 1:50 | null |
| IP | 1:50 | null |
Background
KIM-1 is a protein the most highly upregulated in injured kidneys by various types of insults. Its upregulation during renal injury has been found in the kidneys of the vertebrates such as Zebrafish and humans. KIM-1 is also a member of the TIM (T cell transmembrane, immunoglobulin, and mucin) gene family, which plays critical roles in regulating immune cell activity especially regarding the host response to viral infection. It is involved in allergic response, asthma, and transplant tolerance.
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Exchange/Return Notes
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