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Description
CCL15/MIP-1δ/LKN-1(68aa) Protein, HumanProduct Specification Species Human Synonyms C C motif chemokine 15; Chemokine CC 2 (HCC 2); Leukotactin 1 (LKN 1); MIP 1 delta; Macrophage inflammatory protein 5 (MIP 5); Mrp 2b; NCC 3; Small inducible cytokine A15; Accession Q16663 Amino Acid Sequence Ser46 Ile113 Expression System E. coli Molecular Weight 7. 4 kDa (Reducing) Purity >95% by SDS PAGE. Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris,
Product Specification
| Species | Human |
| Synonyms | C-C motif chemokine 15; Chemokine CC-2 (HCC-2); Leukotactin-1 (LKN-1); MIP-1 delta; Macrophage inflammatory protein 5 (MIP-5); Mrp-2b; NCC-3; Small-inducible cytokine A15; |
| Accession | Q16663 |
| Amino Acid Sequence | Ser46-Ile113 |
| Expression System | E.coli |
| Molecular Weight | 7.4 kDa (Reducing) |
| Purity | >95% by SDS-PAGE. |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM Tris, 300mM NaCl, pH8.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | BMC Genomics . 2008 May 15:9:222. |
Background
MIP-1δ, a member of the CC chemokine family, is known for its role in regulating immune responses and inflammation. It functions as a chemoattractant for various immune cells, including monocytes, dendritic cells, and lymphocytes, by binding to its cognate receptor, CCR1. This interaction leads to the recruitment of immune cells to sites of inflammation or infection.
In addition to its chemotactic properties, MIP-1δ has been implicated in modulating immune cell activation and differentiation. It can influence the polarization of T cells towards specific effector phenotypes, such as Th1 or Th2 cells, by regulating the expression of cytokines and chemokines. MIP-1δ is also involved in the regulation of inflammatory responses and has been linked to the pathogenesis of inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease.
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4.4 ★★★★★
Based on 10 reviews
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Product Reviews
★★★★★ 5
Stays put and dissolves slowly. Orange flavor is nice.
If you have to use something overnight for dry mouth definitely get these. I use one nightly with my mouth guard. The orange flavor is very nice and it dissolves slowly overnight. It's small enough to do the trick, but not be overpowering. It stays put. And it works. Definitely notice the improvement inside my mouth.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 13, 2025
★★★★★ 5
This is a seminal book on psychotherapy. A must have!
Format: Hardcover
In the age of virtual (dis)connection, concerning high rates of depression and anxiety, and the importance of self-reliance and individualism, this book comes as a lighthouse of hope and direction. Attachment Theory in Practice is a must-have for any therapist who is looking to deepen their work and bring desired transformation and change to their clients’ lives.
The book provides a beautiful overview of the current state of the mental health field and the need for focusing on emotion, attachment and connection in psychotherapy. Dr. Johnson reminds us that “in order to shape optimal regulation that allows clients to harness their emotions for growth and aliveness, therapists have to ensure that clients are actively engaged with an emotional reality.” She echoes the findings from research on emotion regulation and suggests that “coregulation, rather than solo self-regulation, is the baseline, normal, and most-efficient strategy for us as social animals.” Dr. Jonson clearly posits that change is an emotional and an interpersonal phenomenon.
The book also outlines very practical guidance to working with couples, individuals, and families using the the attachment framework and EFT. As a therapist who is interested in science and empiricism, I am delighted to see the tremendous amount of research support EFT for couples has received over the past decade and I look forward to learning more about the findings in the areas of EFIT and EFFT.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 1, 2019
★★★★★ 5
A Foundational Book in EFT
Format: Hardcover
In a field of books about EFT, Sue Johnson’s new book provides an up-to-date summary of the latest developments in the EFT method, including applications for individual, couple and family therapy. Having been a student of EFT for 12 years or more, this book was more than a repetition of the fundamentals of the method, its stages and steps, which appear in her earlier books and have been elaborated by other authors. Here, I found her efforts to situate EFT conceptually in the field of psychotherapy, not only its attitude toward defining health and distress, but the underlying principles for its attitude toward how change occurs and its unique principles for how therapists help clients (individual, couple or family) foster change in themselves and their lives. She explains and illustrates the use of the EFT Tango moves, which implement the EFT method within the clinical dialogue and actualize the change process. No doubt, this book will become a primary source for future EFT training and is worth both reading and mastering cover-to-cover.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 21, 2019
★★★★★ 5
Broadens EFT Couple frame to individual and family work
Format: Hardcover, Format: Hardcover
I am really digging in to this. Even though it is an academic book, I find it highly readable and pragmatic. I am chewing slowly on pieces and am using my attachment TANGO (read the book) with my individual clients to great effect. Previously I would use an attachment frame but it wasn’t as focused and organized. Really an orienting perspective. Of course I am also integrating this precisely written guide with my couples, as I am an EFT couple therapist. And for classroom teaching the first few chapters alone highlight—and back up with research the reliability of attachment as a unifying frame. I call it my “map for human” and it
Really is. Thank you Sur for putting all that research in one place.
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Reviewed in the United States on February 15, 2019
★★★★★ 5
Love this book!!
Format: Hardcover
Sue Johnson has done it again! She is on the cutting edge of Attachment Science and is leading the way in helping us humans join other humans on our journey of healing! As a therapist, she has impacted how I work and practice the art of connecting. Thanks Sue!! Great job! This book has expanded Emotionally Focused Therapy so that no one is missing out.... individuals, couples, and families can all be impacted by the process of emotional resonance, regulation and revision. Thank you!
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Reviewed in the United States on July 21, 2019
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