Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 17 - Aug 22
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Stat5b Recombinant Rabbit mAb (S-2951-34)Product Specification Host Rabbit Antigen Stat5b Synonyms Signal transducer and activator of transcription 5B Immunogen Recombinant Protein Location Cytoplasm, Nucleus Accession P42232 Clone Number S 2951 34 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Positive Sample K562, HeLa, Jurkat, Raji, Daudi, NIH 3T3, RAW264. 7, mouse heart, PC 12, rat heart Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Antigen | Stat5b |
| Synonyms | Signal transducer and activator of transcription 5B |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm, Nucleus |
| Accession | P42232 |
| Clone Number | S-2951-34 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | K562, HeLa, Jurkat, Raji, Daudi, NIH/3T3, RAW264.7, mouse heart, PC-12, rat heart |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Hu, Ms, Rt |
| IHC-P | 1:2000 | Hu, Ms, Rt |
| ICC | 1:500 | Ms |
Background
Stat5b (signal transducer and activator of transcription 5b) is a 787-amino-acid transcription factor that, upon phosphorylation by JAK kinases in response to cytokines such as IL-2, GH, prolactin or IFN-α, dimerizes and translocates to the nucleus where it binds the consensus GAS motif TTCNNNGAA to regulate genes controlling cell survival, proliferation, differentiation and metabolic reprogramming; it is indispensable for normal immune homeostasis, mammary gland development and liver GH signaling, and its persistent activation is a driver of multiple hematologic and solid cancers, making Stat5b a validated therapeutic target.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy