SKU: 70539744257

SIALLAC Gut Health - Made in USA - Gut Barrier Function, Epithelial Cell Growth, Immune Support, Enhances Nutrient Absorption, Microbiome Balance (HMO 3'-SL)

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Description

SIALLAC Gut Health - Made in USA - Gut Barrier Function, Epithelial Cell Growth, Immune Support, Enhances Nutrient Absorption, Microbiome Balance (HMO 3'-SL)Gut Mucosal Defense Function: 3' SL enhances the expression of tight junction proteins (ZO 1, Occludin) in the gut lining. These proteins play a primary role in strengthening the gut mucosal barrier, help maintain the integrity of the gut lining, and promoting overall gut health (DOI: 10. 1186 s40104 022 00673 8) Gut Epithelial Cells Growth: 3' SL enhances the expression of Ki67 protein, a marker of cell proliferation, leading to improved crypt villus

  • Gut Mucosal Defense Function: 3'-SL enhances the expression of tight junction proteins (ZO-1, Occludin) in the gut lining. These proteins play a primary role in strengthening the gut mucosal barrier, help maintain the integrity of the gut lining, and promoting overall gut health (DOI:10.1186/s40104-022-00673-8)
  • Gut Epithelial Cells Growth: 3'-SL enhances the expression of Ki67 protein, a marker of cell proliferation, leading to improved crypt-villus integrity and increased gut epithelial cell growth. These celss play a crucial role in gut health by absorbing nutrients, protecting the gut barrier, performing secretion functions, improving gut motility for smoother bowel movements, and supporting a healthy digestive system. (DOI: 10.1007/s12035-019-1628-9)
  • Short-Chain Fatty Acids Production: 3'-SL boosts the production of short-chain fatty acids. These fatty acids, like butyrate, propionate and acetate, are key components and energy sources for the gut lining. They help fortify the gut lining and enhance its primary defense function, while also supporting the overall health of gut epithelial cells (DOI: 10.3390/microorganisms12020252)
  • Digestive Function Improvement: 3'-SL enhances digestive function by activating enzymes like sucrase, maltase, and latase to break down carbohydrates more effectively. It also improves the gut lining by increasing the height of villi in the jujunum and ileum, expanding the absorption area. These actions help the body absorb nutrients more effectively, providing more energy from food (DOI: 10.1016/j.jff.2024.106215)
  • Gut Barrier & Mucosal Defense: 3'-SL enhances the defense capability of the gut mucosa. It aids in the proliferation of gut epithelial cells, creating a stronger gut lining. (DOI: 10.1128/iai.65.2.750-757.1997)
  • 3'-SL supports the natural integrity of the gut lining by encouraging the growth of beneficial cells in the intestinal wall. A healthy gut lining plays a key role in maintaining digestive balance and overall gut wellness.
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SKU: 70539744257

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4.8 ★★★★★
Based on 20 reviews
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Verified Purchase
Stormy
Houston, US
★★★★★ 1
Less than 1
Size: Medium (Pack of 1)
I purchased a Kong Extreme Dog Toy at Tractor Supply and it lasted for several weeks with no signs of damage and then my dog lost it. So I went on the search for more Kong Extreme toys for powerful chewers on Amazon. I have a 60 lb. American Straffordshire Pit and he is a fierce chewer. Most chew toys can make it for a day with some damage but by day 2 the fun is over. For him because the toy is torn to bits and for me because I have to pick up the remnants. I have learned not to get him anything fuzzy - he will rip the fuzz off and I have learned not to get him anything with a squeaker because he will not stop chewing until he finds the squeaker and rip it out. He had the end of the Kong Extreme Goodie Bond Dog Toy off in less than 30 minutes and that was alternating between the Wubba toy for fetching and the bone for chewing, I can tell the Wubba isn't going to last anytime if I let him sit down and chew on it so I had to keep taking it away from him. He likes to catch but he doesn't like to fetch. When I took the bone out of the package I was more worried about the center as it seemed very flimsy and I had doubts it would make it but my dog concentrated on the holes on the ends (with no snacks in them) and when he laid down to chew on it, he was able to rip the end off in a matter of minutes, This is also listed as for power chewers. I have other Kong toys I have ordered for him because he loves to play and chew but I can hardly afford to pay $8 to $10 per toy for him to have half a hour of chewing fun. I went back to TSC for a Kong Extreme Dog Toy and I tried one of the classic Kongs. The classic had one end missing in less than an hour. A Pit Bull breeder said the only thing he has found his dogs can play with and not destroy are bowling balls. He keeps his dogs in kennels and in a barn and my dog is a house dog so since I don't live in a bowling alley I know that I would wind up wishing he would only chew it up instead of roll it into every piece of furniture or a wall. I had such high hopes for the Kong Extreme but it is said to have a dog get attached to a toy then have to take it away from him every ten to fifteen minutes because a power chew toy can't hold up to chewing. Off to find an alternative to Kong,,,,, one toy out of five holding up is not a good recommendation and very expensive to try to find something the dog can enjoy and not destroy.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 28, 2014
E
Verified Purchase
Ellen R.
Pawtucket, US
★★★★★ 5
Safest dog toy .
Size: X Large
It really is the most durable ! My 160lbs mastiff loves it .
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 4, 2026
T
Verified Purchase
Tara R Applegate
Grantham, US
★★★★★ 1
Terrible item
My dog has already torn up one of the dogs. Just gave it to her today. I do not recommend this item
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Reviewed in the United States on June 13, 2026
D
Verified Purchase
Dee S
Waukegan, US
★★★★★ 5
Soft and durable !!
These cute toys have held up better than any of the other 20 toys Max has had!!!
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Reviewed in the United States on June 14, 2026
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Verified Purchase
Brenda
Alexandria, US
★★★★★ 1
Cute but tore apart quickly
They’re really cute. But, my small dog tore them apart in about 5 minutes.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 12, 2026

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