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Description
PKC beta Recombinant Rabbit mAb (S-3158-28)Product Specification Host Rabbit Antigen PKC beta Synonyms Protein kinase C beta type; PKC B; PKC beta; PKCB; PRKCB1; PRKCB Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession P05771 Clone Number S 3158 28 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu, Ms, Rt Positive Sample K562, THP 1, mouse brain, rat brain Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | PKC beta |
| Synonyms | Protein kinase C beta type; PKC-B; PKC-beta; PKCB; PRKCB1; PRKCB |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | P05771 |
| Clone Number | S-3158-28 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | K562, THP-1, mouse brain, rat brain |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
Background
Protein kinase C beta (PKCβ) is a serine/threonine kinase of the conventional PKC subfamily that is activated by diacylglycerol and calcium; it phosphorylates diverse substrates to regulate glucose transport, vascular permeability, immune cell signaling and cell survival, and its sustained overactivity drives diabetic microvascular complications, atherosclerosis and certain cancers, making selective PKCβ inhibitors attractive therapeutic candidates.
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