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Description
CD105 Recombinant Rabbit mAb (S-3764-11)Product Specification Host Rabbit Antigen CD105 Synonyms Endoglin; Cell surface MJ7 18 antigen; Edg; Eng Immunogen Synthetic Peptide Location Cell membrane Accession Q63961 Clone Number S 3764 11 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Ms, Rt Positive Sample bEnd. 3 Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03%
Product Specification
| Host | Rabbit |
| Antigen | CD105 |
| Synonyms | Endoglin; Cell surface MJ7/18 antigen; Edg; Eng |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | Q63961 |
| Clone Number | S-3764-11 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Ms, Rt |
| Positive Sample | bEnd.3 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500-1:1000 | Ms, Rt |
| IHC-P | 1:2000 | Ms, Rt |
Background
CD105, also known as Endoglin, is a type I transmembrane glycoprotein and a component of the transforming growth factor-beta (TGF-β) receptor complex. It is highly expressed in proliferating endothelial cells and plays a crucial role in angiogenesis and vascular development. CD105 is upregulated in areas of active vascular growth, such as tumor tissues, wound healing sites, and inflamed tissues, making it a valuable marker for studying tumor-related angiogenesis. Additionally, it is involved in maintaining the integrity of the vascular system and regulating immune responses. In clinical applications, CD105 is used as a diagnostic marker for certain cancers and vascular diseases, and it is also a potential target for anti-angiogenic therapies.
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Exchange/Return Notes
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