SKU: 72683160909

FITC Mouse Anti-Human/Mouse ZAP-70 Antibody (S-R678)

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Description

FITC Mouse Anti-Human/Mouse ZAP-70 Antibody (S-R678)Product Specification Host Mouse Antigen ZAP 70 Synonyms Tyrosine protein kinase ZAP 70; 70 kDa zeta chain associated protein; Syk related tyrosine kinase; SRK; ZAP70 Location Cytoplasm, Cell membrane Accession P43403P43404 Clone Number S R678 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu, Ms Positive Sample Human PBMC Purification Protein G Concentration 0. 02mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS,

Product Specification


Host Mouse
Antigen ZAP-70
Synonyms Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase; SRK; ZAP70
Location Cytoplasm, Cell membrane
Accession P43403、P43404
Clone Number S-R678
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu, Ms
Positive Sample Human PBMC
Purification Protein G
Concentration 0.02mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
ICFCM 5μl per million cells in 100μl volume Hu, Ms

Background

ZAP-70 (Zeta-chain-associated protein kinase 70) is a cytoplasmic protein tyrosine kinase that plays a crucial role in T cell receptor (TCR) signaling and is essential for T cell activation and development. It is primarily expressed in T cells, natural killer cells, and a subset of B cells. When the TCR binds to an antigen, the tyrosine kinase Lck is activated, phosphorylating the immunoreceptor tyrosine-based activation motifs (ITAMs) on the CD3 complex. These phosphorylated ITAMs serve as docking sites for ZAP-70, which is then activated and phosphorylates downstream molecules such as the linker for activation of T cells (LAT) and the SH2-domain-containing leukocyte protein of 76 kDa (SLP-76). This cascade of events leads to T cell activation, proliferation, and differentiation. In addition, ZAP-70 expression in B cells is associated with chronic lymphocytic leukemia (CLL), making it a potential biomarker and therapeutic target.

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SKU: 72683160909

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4.8 ★★★★★
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Jana Caudill
Port Orchard, US
★★★★★ 5
Don’t judge by the size
Color: White, Size: Standard (Pack of 2)
I don’t write reviews here typically but I’ve been on the pillow hunt for years with no luck. Mine are always lumpy and misshapen or too soft or too firm. Don’t judge this pillow by how it looks though because I saw it and thought for sure I wasted money. They are small and not fluffy at all. But OMG I laid down on it and it’s the most comfortable pillow I’ve had in years. Memory foam didn’t work for me but this simple little pillow just allowed me some great sleep. Very happy with this purchase. It’s a simple, no frills pillow that’s perfect for this side sleeper that doesn’t like a too soft pillow.
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Reviewed in the United States on April 11, 2026
M
Verified Purchase
Missis Staples
Los Angeles, US
★★★★★ 5
Superb!!!!
Color: White, Size: Queen (Pack of 4)
If I could give more than 5 stars I would. I purchased these beauties 6 months ago and they are still fluffy and firm. I'm amazed by the price point. I will definitely re-order for the guess bedroom.
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Reviewed in the United States on May 24, 2026
S
Verified Purchase
SimplyGG
Port Orchard, US
★★★★★ 4
Soft and comfortable, NOT firm.
Color: White, Size: Queen (Pack of 2), Color: White, Size: Queen (Pack of 2)
Overall, these are comfortable pillows for the price, especially if you prefer something soft rather than firm. The pillows arrived vacuum sealed, which is pretty standard. Once opened, they fluffed up well after some time and looked full enough to use. Right away, they felt soft and plush, and sleeping on them was comfortable from the first night. In terms of comfort and support, these pillows are definitely on the softer side. They work well for side and back sleeping if you like a pillow that you can sink into a bit. They’re not firm or dense, but they’re still cozy and gentle on the neck and head. After a few days of use, I did notice that the pillows started to look a little lumpy and uneven. The filling tends to shift, so they don’t hold their shape perfectly and need regular fluffing. That said, even when they look a bit misshapen, they’re still soft and comfortable to sleep on. If you’re someone who needs strong neck support or prefers a firm hotel-style pillow, these may feel too soft. However, if comfort and plushness are your priority, they do the job well. For the price, I think they’re a good value. They’re not luxury pillows, but they’re comfortable, decent quality, and perfectly fine for everyday use or a guest bed.
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Reviewed in the United States on January 5, 2026
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Verified Purchase
Bernell M David
Alexandria, US
★★★★★ 5
Nice and comfortable as it is light and supportive in all positions
Color: White, Size: Standard (Pack of 2)
Beautiful light pillows that will absolutely provide the comfort and easiness towards a great night of sleep!
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Reviewed in the United States on May 27, 2026
S
Verified Purchase
Skania19
West Palm Beach, US
★★★★★ 5
Would buy again
Color: White, Size: Standard (Pack of 2)
This is a good pillow if you like them firm and thin. I let them sit out for 2 days (per instructions). After having them a week, they've perked up and became more full. I guess they just need time after being in the air. They are softer now but your head doesn't sink thru it. They are actually nice and soft to the touch as well.
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Reviewed in the United States on May 4, 2026

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