Pay in installments of $33.75 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 3 - Sep 8
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
APC-Cy7 Rat Anti-Mouse CD49b Antibody (S-R543)Product Specification Host Rat Antigen CD49b Synonyms Integrin alpha 2; CD49 antigen like family member B; Collagen receptor; Platelet membrane glycoprotein Ia (GPIa); VLA 2 subunit alpha; Itga2 Location Membrane Accession Q62469 Clone Number S R543 Antibody Type Rat mAb Isotype IgM Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation APC Cy7 Physical Appearance Liquid
Product Specification
| Host | Rat |
| Antigen | CD49b |
| Synonyms | Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia (GPIa); VLA-2 subunit alpha; Itga2 |
| Location | Membrane |
| Accession | Q62469 |
| Clone Number | S-R543 |
| Antibody Type | Rat mAb |
| Isotype | IgM |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | APC-Cy7 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD49b, also known as integrin alpha-2, is a protein encoded by the CD49b gene in humans. It is a subunit of the integrin receptor family, specifically forming the VLA-2 receptor when paired with the beta-1 subunit. This receptor is primarily involved in mediating cell adhesion to collagen and laminin, playing a crucial role in various biological processes such as platelet aggregation, cell migration, and tissue repair. CD49b is expressed on various cell types, including natural killer cells and a subset of T cells, and has been implicated in immune responses and cancer progression. In cancer research, CD49b has been identified as a potential therapeutic target due to its role in promoting cell proliferation and invasion in certain malignancies.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy