SKU: 73657165736

Armenian hamster Anti-Human/Mouse/Rat CD278 Antibody (S-R578)

$90.00 $100.00
Save 10%
No.2 Bestseller on 2pierres.com >

Pay in installments of $25.00 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Sep 8 - Sep 13

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Armenian hamster Anti-Human/Mouse/Rat CD278 Antibody (S-R578)Product Specification Host Armenian hamster Antigen CD278 Synonyms Inducible T cell costimulator; Activation inducible lymphocyte immunomediatory molecule; AILIM; ICOS Location Cell membrane Accession Q9Y6W8 Clone Number S R578 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Hu, Ms, Rt Positive Sample Human PBMC Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7.

Product Specification


Host Armenian hamster
Antigen CD278
Synonyms Inducible T-cell costimulator; Activation-inducible lymphocyte immunomediatory molecule; AILIM; ICOS
Location Cell membrane
Accession Q9Y6W8
Clone Number S-R578
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Hu, Ms, Rt
Positive Sample Human PBMC
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:2000 Hu

Background

CD278, also known as ICOS (inducible T-cell costimulator), is a costimulatory receptor belonging to the CD28 family, mainly expressed on activated CD4 and CD8 T cells, and weakly expressed on naïve T cells. It is a type-1 transmembrane molecule with a single Ig V-like domain, a transmembrane region of 23 amino acids, and a cytoplasmic domain of 35 amino acids. Structurally, it is similar to CD28 and CTLA-4 but lacks the MYPPPY motif found in CD28, which is critical for binding to B7-1 and B7-2. ICOS plays a crucial role in T cell activation and differentiation, particularly in the development and maintenance of T follicular helper (Tfh) cells. It is also involved in the regulation of cytokine production and cell motility, promoting the migration of T cells to the follicle. Additionally, ICOS signaling can induce the expression of CXCR5 and Bcl6, and suppress the expression of CCR7, PSGL-1, and CD62L through the factor KLF2.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 73657165736

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.5 ★★★★★
Based on 30 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
A
Verified Purchase
Auskan
Carnegie, US
★★★★★ 5
Worth the money
Size: Medium (Pack of 2), Color: Assorted
I've had several sizes of Chuck-It ball launchers for years but had resisted buying the balls to go with them because I had about 50 tennis balls already that cost only pennies apiece and these were quite a bit more expensive. But, I got tired of the dogs chewing up the tennis balls. I'd start a ball throwing session with a brand new ball and for the first few throws it would sail through the air and the dogs would have to work to retrieve it. However on the way back, their jaws would work it, chomp-chomp-chomp. And when they returned to me, they'd want to stand there and chomp some more, despite my command to "Drop it!" Within 30 minutes, the brand new ball would have a hole in it and then instead of sailing several football fields through the air, then bouncing over a couple of trees, I'd throw it and it would piddle unenthusiastically to the end of the driveway before falling to the ground with a sulky thud, not even bothering to bounce. So - I finally grew tired of going through a ball every time I play with the dogs - which is everyday - and ordered these chuck-it balls. They are the same size as a tennis ball but made of a rubber-like material (not silicone) and after several months of use, have no wear and tear on them at all. The dogs can exercise their gums on them all the way back to me - throw after throw - and the ball still flies the same distance each time, and bounces satisfyingly upon contact with the ground. The description says "colors may vary" but the first packet I ordered were blue and orange as pictured. Unfortunately my dog lost the orange one the first time we used it. She got thirsty and ran down to our pond for a drink, dropped the ball in the pond and it hasn't been seen since. It is dense enough it doesn't float as a tennis ball might, and by now is probably so covered in mud and slime that I wouldn't recognize it if I tripped over it. Lesson learned: we don't throw the ball in the pond pasture any more. After losing the orange ball, I ordered a second packet of the balls so that I would always have a spare. The second packet is also blue and orange. So while colors may vary, in my experience so far, they haven't (which doesn't matter to me or the dogs).
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 1, 2015
D
Verified Purchase
Dawn T Conway
San Leandro, US
★★★★★ 5
Super Chewer Friendly!!
Size: Large (Pack of 1), Color: Multi
This ball is perfect for the super Chewer!! It is squishy and durable rubber that stands up to the aggressive chewer. It does not squeak. It has great bounce and is a great toy for fetch. Very cute to watching my pup bring the ball back for another throw. The rubber doesn't stick or have an average powering smell. It smells just like a rubber ball. It is highly functional for a great game of fetch! Highly recommend and very happy with our purchase. It is well worth the price. We will be ordering more.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 20, 2025
M
Verified Purchase
marie johnson
Cuba, US
★★★★★ 5
Quality
Color: Gold
Very good
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 25, 2026
T
Verified Purchase
tyrone_shulaysis
Waukegan, US
★★★★★ 5
quality
Color: Gold
Great quality.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 15, 2026
J
Jill Nicely
Omaha, US
★★★★★ 4
so elegant but best for softer foods
Color: Gold, Color: Gold
I am impressed with this gold silverware. I was surprised because they are very light, but they are also elegant. The handles are a little longer than the usual plasticware, so holding them, using them to eat, made me feel like the meal was elevated. These would be perfect at a garden party, a brunch, a fancy picnic. I love that there are equal numbers of knives, forks, and spoons, and they would look beautiful at place settings, or just tossed into glasses for people to grab what they need. My one misgiving about recommending these for any occasion is the knife. It’s just not sharp, and like the other pieces, it is lightweight. It’s great for spreading butter onto a roll and could cut through soft foods like pasta or cake. But any attempt to cut through a piece of meat or a starchy vegetable that’s just lightly cooked will result in the knife snapping in half. But if you’re serving relatively soft foods (brunch would be perfect!), then this is an elegant, easy solution to feed a lot of people while keeping cleanup to a minimum.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 7, 2026

recommand products

WATER TEMP SENSOR (AT-01362)
28.95
BRONCO UNIVERSAL JOINT (AT-08518)
34.95
BRONCO HD AXLE HONDA (HON-6051HD)
129.97
BRONCO OIL FILTER (MC-07155)
12.95
BRONCO AXLE KAWASAKI (KAW-7023)
169.95