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Description
CD1c Recombinant Rabbit mAb (S-2008-38)Product Specification Host Rabbit Antigen CD1c Synonyms T cell surface glycoprotein CD1c; CD1C Immunogen Synthetic Peptide Location Lysosome, Cell membrane Accession P29017 Clone Number S 2008 38 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample Jurkat, Molt 4 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03%
Product Specification
| Host | Rabbit |
| Antigen | CD1c |
| Synonyms | T-cell surface glycoprotein CD1c; CD1C |
| Immunogen | Synthetic Peptide |
| Location | Lysosome, Cell membrane |
| Accession | P29017 |
| Clone Number | S-2008-38 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Positive Sample | Jurkat, Molt-4 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
Background
CD1c is a member of the CD1 family of transmembrane glycoproteins that are structurally related to major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. It is involved in the presentation of lipid and glycolipid antigens of self or microbial origin to T cells. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. CD1c is highly expressed in dendritic cells and is also found in other immune-related tissues. It plays a role in adaptive immunity, tissue homeostasis, and autoimmune diseases.
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