SKU: 76258304736

Phospho-GSK-3β (Ser9) Recombinant Rabbit mAb (S-748-20)

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Description

Phospho-GSK-3β (Ser9) Recombinant Rabbit mAb (S-748-20)Product Specification Host Rabbit Synonyms Glycogen synthase kinase 3 beta; Serine threonine protein kinase GSK3B; GSK3B Immunogen Synthetic Peptide Location Cytoplasm Accession P49841 Clone Number S 748 20 Antibody Type Recombinant mAb Isotype IgG Application WB, IP Reactivity Hu, Ms, Rt Predicted Reactivity Ms, Rt, Sq, Xe Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40%

Product Specification


Host Rabbit
Synonyms Glycogen synthase kinase-3 beta; Serine/threonine-protein kinase GSK3B; GSK3B
Immunogen Synthetic Peptide
Location Cytoplasm
Accession P49841
Clone Number S-748-20
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IP
Reactivity Hu, Ms, Rt
Predicted Reactivity Ms, Rt, Sq, Xe
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20°C as supplied

Dilution


application dilution species
Dot Blot 1:1000
WB 1:1000
IP 1:50

Background

GSK-3 is a serine/threonine protein kinase that phosphorylate either threonine or serine, and this phosphorylation controls a variety of biological activities, such as glycogen metabolism, cell signaling, cellular transport, and others. GSK-3 has also been shown to regulate immune and migratory processes. GSK-3 participates in a number of signaling pathways in the innate immune response, including pro-inflammatory cytokine and interleukin production. GSK-3 is also integrally tied to pathways of cell proliferation and apoptosis. GSK-3 has been shown to phosphorylate Beta-catenin, thus targeting it for degradation. GSK-3 is therefore a part of the canonical Beta-catenin/Wnt pathway, which signals the cell to divide and proliferate. Insulin indirectly inactivates GSK3 via downstream phosphorylation of the specific serine residues Ser21 and Ser9 in GSK-3 isoforms α and β, respectively, via the PI3K/Akt pathway (protein kinase B).

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SKU: 76258304736

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JJ Fording
West Palm Beach, US
★★★★★ 5
Balls
Size: Medium
My dog loves chasing these balls. He seems to love the squeak! They fit the chuck it stick perfectly, and are great replacements for the originals that came with the stick.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 7, 2026
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Steve just Steve
Cuba, US
★★★★★ 5
Nice set of balls
Size: Medium
The squeaker quickly became my dog’s favorite ball and has replaced the fuzzy tennis balls. My dog is a nonstop fetcher and these chuck it balls are durable and fun.
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Reviewed in the United States on January 9, 2026
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Verified Purchase
Claudia Garfield
Fort Morgan, US
★★★★★ 5
Perfect ball
Size: Medium
Our dog loves these!
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Reviewed in the United States on May 26, 2026
T
Verified Purchase
Timothy john starkweather
Natrona Heights, US
★★★★★ 4
Soild
Size: Medium
The orange and blue ball is perfect. Once start taken because the because the blue noisy one was a little to easy for my dog to start ripping pieces off. Will say most toys do not survive his chewing.
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Reviewed in the United States on January 24, 2026
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Verified Purchase
Christy D.
Los Angeles, US
★★★★★ 5
Aggressive chewer who loves fetch approved!!
Size: Medium, Size: Medium
I highly recommend the Chuck-It brand in general, especially for dogs with an aggressive bite. These balls are awesome and are the most durable balls I’ve bought for my 50 lbs lab mix. He has not been able to break one of them yet and we’ve had a few of the squeaky balls for months. They are a bit pricey but worth it. The one in the pic has been used for months, lives outside and you can see it’s still in great shape.
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Reviewed in the United States on June 22, 2025

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