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Description
ACSL4/FACL4 Recombinant Rabbit mAb (S-461-6)Product Specification Host Rabbit Antigen ACSL4 FACL4 Synonyms Long chain fatty acid CoA ligase 4, Arachidonate CoA ligase, Long chain acyl CoA synthetase 4 (LACS 4), ACS4 Immunogen Synthetic Peptide Location Cell membrane, Endoplasmic reticulum membrane, Mitochondrion outer membrane Accession O60488 Clone Number S 461 6 Antibody Type Recombinant mAb Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5
Product Specification
| Host | Rabbit |
| Antigen | ACSL4/FACL4 |
| Synonyms | Long-chain-fatty-acid--CoA ligase 4, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 4 (LACS 4), ACS4 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane, Endoplasmic reticulum membrane, Mitochondrion outer membrane |
| Accession | O60488 |
| Clone Number | S-461-6 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC | 1:200-1:500 | |
| ICC | 1:500 | |
| ICFCM | 1:500 |
Background
ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the intellectual disability or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
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