SKU: 77401650556

S-RMab® MSH6 Recombinant Rabbit mAb,PBS Only (SDT-R094)

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Description

S-RMab® MSH6 Recombinant Rabbit mAb,PBS Only (SDT-R094)Product Specification Host Rabbit Antigen MSH6 Synonyms hMSH6,GTBP Immunogen N A Location Nucleus Accession P52701 Clone Number SDT R094 Antibody Type Rabbit mAb Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt, 4C as supplied Dilution application dilution species WB 1: 1000 Hu, Ms IHC P 1: 500 Hu, Ms, Rt ICC 1:

Product Specification


Host Rabbit
Antigen MSH6
Synonyms hMSH6,GTBP
Immunogen N/A
Location Nucleus
Accession P52701
Clone Number SDT-R094
Antibody Type Rabbit mAb
Application WB, IHC-P, ICC
Reactivity Hu, Ms, Rt
Purification Protein A
Concentration 1 mg/ml
Physical Appearance Liquid
Storage Buffer

PBS

Stability & Storage

12 months from date of receipt, 4°C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms
IHC-P 1:500 Hu, Ms, Rt
ICC 1:500 Hu

Background

DNA mismatch repair protein (MSH6) is one of the mismatch repair proteins and is encoded by the MSH6 gene, which is located on chromosome 2 and is 23,806 bp in length, including 10 exons and 83 untranslated regions. The MSH6 protein consists of 1,358 amino acid residues and forms a heterodimer with another mismatch repair protein, MSH2. The MSH2-MSH6 heterodimeric complex is able to recognize base-base substitution and single-base insertion/deletion mismatches. Germline mutations of MSH6 lead to high susceptibility to glioma, as well as a number of benign or malignant tumors in other organs.

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SKU: 77401650556

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